Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | TSHR | P16473 | 3/20 | 0.32 |
| ▸ | USP2 | O75604 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 2/20 | 0.31 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7808250 | 0.74 | MAPK1 (0.41) | MAPK1MEN1KMT2AHSD17B10CYP3A4 | |
| SCHEMBL5415021 | 0.74 | MAPK1 (0.48) | MAPK1MEN1KMT2AALDH1A1HPGD | |
| SCHEMBL5071115 | 0.73 | MAPK1 (0.46) | MAPK1MEN1KMT2A | |
| SCHEMBL5317376 | 0.72 | SMN1; SMN2 (0.42) | MAPK1MEN1KMT2ASMN1; SMN2TSHR | |
| SCHEMBL6997536 | 0.71 | MAPK1 (0.38) | MAPK1MEN1KMT2A | |
| SCHEMBL10215944 | 0.71 | SMN1; SMN2 (0.47) | SMN1; SMN2TSHRUSP2ALDH1A1POLB | |
| SCHEMBL7804700 | 0.69 | MAPK1 (0.44) | MAPK1MEN1KMT2AALDH1A1 | |
| SCHEMBL10215961 | 0.69 | CYP1A2 (0.40) | SMN1; SMN2TSHRALDH1A1NPC1CYP3A4 | |
| SCHEMBL124787 | 0.67 | GAA (0.42) | SMN1; SMN2TSHRUSP2ALDH1A1POLB | |
| SCHEMBL7748021 | 0.66 | NPC1 (0.37) | SMN1; SMN2TSHRALDH1A1NPC1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0946553-A1 | 8-AZABICYCLO 3.2.1]OCTANE DERIVATIVES, THEIR PREPARATION AND THEIR USE AS INSECTICIDES | ZENECA LIMITED (GB) | 1999-10-06 | — | — | EP | disclosed |
| WO-1998025923-A1 | 8-AZABICYCLO[3.2.1]OCTANE DERIVATIVES, THEIR PREPARATION AND THEIR USE AS INSECTICIDES | ZENECA LIMITED (GB) | 1998-06-18 | — | — | WO | disclosed |