Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 3/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.35 |
| ▸ | OPRD1 | P41143 | 2/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | FKBP1A | P62942 | 1/20 | 0.30 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.30 |
| ▸ | RECQL | P46063 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7804700 | 0.81 | MAPK1 (0.44) | MAPK1MEN1KMT2AOPRM1OPRD1 | |
| SCHEMBL5415021 | 0.79 | MAPK1 (0.48) | MAPK1MEN1KMT2AOPRM1OPRD1 | |
| SCHEMBL5071115 | 0.78 | MAPK1 (0.46) | MAPK1MEN1KMT2A | |
| SCHEMBL7809891 | 0.78 | LMNA (0.33) | OPRM1OPRD1CYP2C19CYP2D6LMNA | |
| SCHEMBL7805795 | 0.76 | LMNA (0.38) | CYP2C19CYP2D6LMNA | |
| SCHEMBL7805796 | 0.76 | LMNA (0.38) | CYP2C19CYP2D6LMNA | |
| SCHEMBL26157415 | 0.74 | LMNA (0.39) | MEN1KMT2ACYP2C19CYP2D6LMNA | |
| SCHEMBL8505608 | 0.74 | MAPK1 (0.36) | MAPK1MEN1KMT2AHSD17B10CYP3A4 | |
| SCHEMBL7808304 | 0.71 | ACHE (0.44) | MAPK1MEN1KMT2AOPRM1OPRD1 | |
| SCHEMBL3645840 | 0.69 | GSK3A (0.45) | MAPK1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0710662-B1 | QUINOLINECARBOXYLIC ACID DERIVATIVE | SYNGENTA LTD (GB) | 2001-04-04 | — | — | EP | disclosed |
| EP-1018513-A2 | Quinolinecarboxylic acid derivatives | ZENECA LIMITED (GB) | 2000-07-12 | — | — | EP | disclosed |
| EP-0710662-A1 | QUINOLINECARBOXYLIC ACID DERIVATIVE | TAISHO PHARMACEUTICAL CO. LTD (JP) | 1996-05-08 | — | — | EP | disclosed |