Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PGR | P06401 | 6/20 | 0.60 |
| ▸ | CYP3A4 | P08684 | 5/20 | 0.60 |
| ▸ | AR | P10275 | 2/20 | 0.60 |
| ▸ | F2 | P00734 | 1/20 | 0.60 |
| ▸ | NR3C1 | P04150 | 5/20 | 0.60 |
| ▸ | HIF1A | Q16665 | 5/20 | 0.60 |
| ▸ | ABCB11 | O95342 | 3/20 | 0.60 |
| ▸ | NR1I2 | O75469 | 2/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.60 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.60 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.60 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.60 |
| ▸ | ABCC3 | O15438 | 1/20 | 0.48 |
| ▸ | CYP19A1 | P11511 | 5/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.45 |
| ▸ | USP2 | O75604 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8505959 | 0.92 | PGR (0.59) | PGRCYP3A4ARF2NR3C1 | |
| SCHEMBL8527279 | 0.91 | ABCB11 (0.53) | PGRCYP3A4ARF2NR3C1 | |
| SCHEMBL8505510 | 0.90 | PGR (0.57) | PGRCYP3A4ARF2NR3C1 | |
| SCHEMBL8505481 | 0.90 | PGR (0.59) | PGRCYP3A4ARF2NR3C1 | |
| SCHEMBL8505975 | 0.90 | PGR (0.60) | PGRCYP3A4ARF2NR3C1 | |
| SCHEMBL20589514 | 0.84 | NR3C1 (0.65) | PGRCYP3A4ARNR3C1HIF1A | |
| SCHEMBL7609790 | 0.84 | NR3C1 (0.65) | PGRCYP3A4ARNR3C1HIF1A | |
| SCHEMBL10902204 | 0.83 | NR3C1 (0.70) | PGRCYP3A4ARF2NR3C1 | |
| SCHEMBL10902192 | 0.83 | NR3C1 (0.70) | PGRCYP3A4ARF2NR3C1 | |
| SCHEMBL6836061 | 0.83 | PGR (0.67) | PGRCYP3A4ARF2NR3C1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5981517-A | FOR TREATING INFLAMMATIONS OF EYES, EARS, SKINS, INTESTINES, MOUTHS, ASTHMA, AND ARTHRITIS IN ANIMALS | SOFT DRUGS, INC. (US) | 1999-11-09 | — | — | US | disclosed |