Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 16/20 | 0.80 |
| ▸ | OPRK1 | P41145 | 12/20 | 0.80 |
| ▸ | OPRD1 | P41143 | 6/20 | 0.80 |
| ▸ | MRGPRX2 | Q96LB1 | 2/20 | 0.57 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.57 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.57 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21008992 | 0.89 | OPRM1 (1.00) | OPRM1OPRK1OPRD1MRGPRX2ADRB1 | |
| SCHEMBL18569385 | 0.89 | OPRM1 (1.00) | OPRM1OPRK1OPRD1MRGPRX2ADRB1 | |
| SCHEMBL30199760 | 0.89 | OPRM1 (1.00) | OPRM1OPRK1OPRD1MRGPRX2ADRB1 | |
| SCHEMBL6865494 | 0.84 | OPRD1 (0.81) | OPRM1OPRK1OPRD1MRGPRX2ADRB1 | |
| SCHEMBL6865490 | 0.84 | OPRD1 (0.81) | OPRM1OPRK1OPRD1MRGPRX2ADRB1 | |
| SCHEMBL14089349 | 0.82 | OPRD1 (0.78) | OPRM1OPRK1OPRD1MRGPRX2ADRB1 | |
| SCHEMBL18569404 | 0.81 | OPRM1 (1.00) | OPRM1OPRK1OPRD1MRGPRX2 | |
| SCHEMBL22838355 | 0.81 | OPRM1 (1.00) | OPRM1OPRK1OPRD1MRGPRX2 | |
| SCHEMBL8383142 | 0.81 | OPRM1 (1.00) | OPRM1OPRK1OPRD1MRGPRX2 | |
| SCHEMBL876355 | 0.81 | OPRM1 (1.00) | OPRM1OPRK1OPRD1MRGPRX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0960111-A1 | MORPHINE DERIVATIVES WITH ANALGESIC ACTIVITY | NYCOMED IMAGING AS (NO) | 1999-12-01 | — | — | EP | disclosed |
| WO-1997022606-A1 | MORPHINE DERIVATIVES WITH ANALGESIC ACTIVITY | NYCOMED IMAGING AS (NO) | 1997-06-26 | — | — | WO | disclosed |