Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 1/20 | 0.37 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.37 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.37 |
| ▸ | BCL2 | P10415 | 1/20 | 0.37 |
| ▸ | BAD | Q92934 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.32 |
| ▸ | CRHR1 | P34998 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8326165 | 0.94 | OPRM1 (0.36) | OPRM1OPRD1OPRK1BCL2BAD | |
| SCHEMBL8329122 | 0.92 | OPRM1 (0.31) | OPRM1OPRD1OPRK1 | |
| SCHEMBL8587701 | 0.90 | GABRB3 (0.38) | OPRM1OPRD1OPRK1BCL2BAD | |
| SCHEMBL8330304 | 0.89 | BCL2 (0.36) | OPRM1OPRD1OPRK1BCL2BAD | |
| SCHEMBL8329405 | 0.89 | BCL2 (0.36) | OPRM1OPRD1OPRK1BCL2BAD | |
| SCHEMBL8328569 | 0.89 | OPRM1 (0.31) | OPRM1OPRD1OPRK1BCL2BAD | |
| SCHEMBL8330780 | 0.86 | CCNE2 (0.38) | OPRM1OPRD1OPRK1BCL2BAD | |
| SCHEMBL8328769 | 0.85 | OPRM1 (0.31) | OPRM1OPRD1OPRK1 | |
| SCHEMBL8329932 | 0.85 | OPRM1 (0.33) | OPRM1OPRD1OPRK1 | |
| SCHEMBL8330873 | 0.85 | OPRM1 (0.31) | OPRM1OPRD1OPRK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0674631-B1 | SUBSTITUTED PYRAZOLES AS CRF ANTAGONISTS | PFIZER (US) | 1999-12-08 | — | — | EP | claimed |