Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | REN | P00797 | 2/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.44 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.44 |
| ▸ | PRMT8 | Q9NR22 | 1/20 | 0.44 |
| ▸ | BACE1 | P56817 | 1/20 | 0.43 |
| ▸ | KCNH2 | Q12809 | 4/20 | 0.42 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11293490 | 0.82 | CARM1 (0.47) | RENCARM1PRMT6PRMT8KCNH2 | |
| SCHEMBL156219 | 0.81 | CARM1 (0.59) | CYP1A2CYP3A4CYP2D6CYP2C9CYP2C19 | |
| SCHEMBL21121016 | 0.81 | CARM1 (0.46) | RENCARM1PRMT6PRMT8KCNH2 | |
| SCHEMBL28789449 | 0.79 | CARM1 (0.49) | RENCARM1PRMT6PRMT8KCNH2 | |
| SCHEMBL11519645 | 0.77 | CHRM2 (0.53) | CARM1PRMT6PRMT8SIGMAR1 | |
| Acetic Acid SCHEMBL28847873 | 0.76 | REN (0.49) | RENCARM1PRMT6PRMT8BACE1 | |
| SCHEMBL10537188 | 0.76 | KCNH2 (0.43) | RENCARM1PRMT6PRMT8BACE1 | |
| SCHEMBL10745991 | 0.75 | CYP1A2 (0.56) | CYP1A2CYP3A4CYP2D6CYP2C9CYP2C19 | |
| SCHEMBL7946214 | 0.74 | KCNH2 (0.42) | RENCARM1PRMT6PRMT8BACE1 | |
| SCHEMBL13937398 | 0.74 | SIGMAR1 (0.52) | KCNH2SIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0907379-A2 | BIOACTIVATED DIAGNOSTIC IMAGING CONTRAST AGENTS | Epix Medical, Inc. (US) | 1999-04-14 | — | — | EP | disclosed |
| WO-1997036619-A2 | BIOACTIVATED DIAGNOSTIC IMAGING CONTRAST AGENTS | EPIX MEDICAL, INC. (US) | 1997-10-09 | — | — | WO | disclosed |