Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKT1 | P31749 | 5/20 | 0.49 |
| ▸ | DAPK3 | O43293 | 1/20 | 0.49 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.49 |
| ▸ | PRKCG | P05129 | 1/20 | 0.49 |
| ▸ | PIM1 | P11309 | 1/20 | 0.49 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.49 |
| ▸ | LIMK1 | P53667 | 1/20 | 0.49 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.49 |
| ▸ | PRKCD | Q05655 | 1/20 | 0.49 |
| ▸ | PAK1 | Q13153 | 1/20 | 0.49 |
| ▸ | STK3 | Q13188 | 1/20 | 0.49 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.49 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.49 |
| ▸ | CDC42BPA | Q5VT25 | 1/20 | 0.49 |
| ▸ | PRKD2 | Q9BZL6 | 1/20 | 0.49 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.49 |
| ▸ | CHRNB2 | P17787 | 3/20 | 0.47 |
| ▸ | CHRNB1 | P11230 | 2/20 | 0.47 |
| ▸ | CHRNB4 | P30926 | 2/20 | 0.47 |
| ▸ | CHRNA3 | P32297 | 2/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL8507893 | 0.99 | AKT1 (0.48) | AKT1DAPK3ROCK2PRKCGPIM1 | |
| SCHEMBL8508215 | 0.94 | CHRNB2 (0.47) | AKT1DAPK3ROCK2PRKCGPIM1 | |
| SCHEMBL8508770 | 0.79 | AKT1 (0.41) | AKT1DAPK3ROCK2PRKCGPIM1 | |
| SCHEMBL6584967 | 0.78 | AKT1 (0.60) | AKT1ROCK2PIM1RPS6KB1PRKCD | |
| SCHEMBL8508030 | 0.77 | CHRNA3 (0.35) | AKT1DAPK3ROCK2PRKCGPIM1 | |
| SCHEMBL6584036 | 0.76 | CHRNB2 (0.69) | AKT1DAPK3ROCK2PRKCGPIM1 | |
| SCHEMBL6233088 | 0.76 | CHRNB2 (0.40) | CHRNB2CHRNB4CHRNA3CHRNA6 | |
| SCHEMBL4779704 | 0.76 | CHRNB2 (0.40) | CHRNB2CHRNB4CHRNA3CHRNA6 | |
| SCHEMBL6236214 | 0.76 | CHRNB2 (0.40) | CHRNB2CHRNB1CHRNB4CHRNA3CHRNB3 | |
| SCHEMBL6234636 | 0.76 | CHRNB2 (0.50) | CHRNB2CHRNB1CHRNB4CHRNA3CHRNB3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0934308-A1 | 3-PYRIDYLOXYMETHYL HETEROCYCLIC ETHER COMPOUNDS USEFUL IN CONTROLLING CHEMICAL SYNAPTIC TRANSMISSION | Abbott Laboratories (US) | 1999-08-11 | — | — | EP | disclosed |
| WO-1997046554-A1 | 3-PYRIDYLOXYMETHYL HETEROCYCLIC ETHER COMPOUNDS USEFUL IN CONTROLLING CHEMICAL SYNAPTIC TRANSMISSION | ABBOTT LABORATORIES (US) | 1997-12-11 | — | — | WO | disclosed |