Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR3A | P46098 | 1/20 | 0.39 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.35 |
| ▸ | HPGDS | O60760 | 1/20 | 0.33 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.33 |
| ▸ | MPO | P05164 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3308039 | 0.88 | HRH4 (0.42) | HRH3HRH4 | |
| Hydrochloric Acid SCHEMBL31404649 | 0.87 | CHRM2 (0.40) | HPGDS | |
| Hydrochloric Acid SCHEMBL949115 | 0.86 | HRH4 (0.41) | HRH3HRH4 | |
| Hydrochloric Acid SCHEMBL9134652 | 0.86 | HRH4 (0.41) | HRH3HRH4 | |
| SCHEMBL27034282 | 0.84 | — | — | |
| SCHEMBL232190 | 0.79 | — | — | |
| SCHEMBL9044336 | 0.75 | — | — | |
| SCHEMBL17604203 | 0.75 | HRH4 (0.36) | HRH3HRH4 | |
| SCHEMBL1786021 | 0.74 | KMO (0.37) | HRH3HRH4 | |
| SCHEMBL8130205 | 0.72 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4559911-A1 | NOVEL HETEROCYCLIC COMPOUND AND PHARMACEUTICAL COMPOSITION FOR INHIBITING AUTOTAXIN COMPRISING THE SAME | Nextgen Bioscience Co., Ltd. (KR) | 2025-05-28 | — | — | EP | disclosed |
| CN-119585265-A | Novel heterocyclic compound and pharmaceutical composition for inhibiting autotaxin comprising same | 株式会社次代生物科学 | 2025-03-07 | — | — | CN | disclosed |
| WO-2024019597-A1 | NOVEL HETEROCYCLIC COMPOUND AND PHARMACEUTICAL COMPOSITION FOR INHIBITING AUTOTAXIN COMPRISING THE SAME | 주식회사 넥스트젠바이오사이언스 | 2024-01-25 | — | — | WO | disclosed |
| WO-1999031089-A1 | 1-(1H-IMIDAZOL-2-YL)PYRROLIDINE AND 1-(1H-IMIDAZOL-2-YLPIPERIDINE) DERIVATIVES, PREPARATION AND THERAPEUTIC APPLICATION | SANOFI-SYNTHELABO (FR) | 1999-06-24 | — | — | WO | disclosed |
| US-5639775-A | COGNITION ACTIVATORS | THE UNIVERSITY OF TOLEDO (US) | 1997-06-17 | — | — | US | disclosed |
| US-5633382-A | Histamine H3 -receptor antagonists and therapeutic uses thereof | THE UNIVERSITY OF TOLEDO (US) | 1997-05-27 | — | — | US | disclosed |
| US-5486526-A | APPETITE SUPPRESSANTS | THE UNIVERSITY OF TOLEDO (US) | 1996-01-23 | — | — | US | disclosed |
| WO-1995011894-A1 | HISTAMINE H3-RECEPTOR ANTAGONISTS AND THERAPEUTIC USES THEREOF | THE UNIVERSITY OF TOLEDO (US) | 1995-05-04 | — | — | WO | disclosed |
| EP-0633882-A1 | 4- 4'-PIPERIDINYL OR 3'-PIRROLIDINYL] SUBSTITUTED IMIDAZOLES AS H3-RECEPTOR ANTAGONISTS AND THERAPEUTIC USES THEREOF | THE UNIVERSITY OF TOLEDO (US) | 1995-01-18 | — | — | EP | disclosed |
| WO-1993020061-A1 | 4-[4'-PIPERIDINYL OR 3'-PIRROLIDINYL] SUBSTITUTED IMIDAZOLES AS H3-RECEPTOR ANTAGONISTS AND THERAPEUTIC USES THEREOF | THE UNIVERSITY OF TOLEDO (US) | 1993-10-14 | — | — | WO | disclosed |