Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1C3 | P42330 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | RECQL | P46063 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | FBP1 | P09467 | 1/20 | 0.43 |
| ▸ | GLA | P06280 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 3/20 | 0.40 |
| ▸ | MTNR1A | P48039 | 2/20 | 0.40 |
| ▸ | MTNR1B | P49286 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.39 |
| ▸ | DHODH | Q02127 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3248323 | 0.84 | AKR1C3 (0.55) | AKR1C3ALDH1A1TSHRRECQLMEN1 | |
| SCHEMBL981803 | 0.84 | AKR1C3 (0.55) | AKR1C3ALDH1A1TSHRRECQLMEN1 | |
| SCHEMBL756714 | 0.83 | ALDH1A1 (0.52) | AKR1C3ALDH1A1TSHRRECQLMEN1 | |
| SCHEMBL28212447 | 0.81 | AKR1C3 (0.48) | AKR1C3ALDH1A1TSHRRECQLMEN1 | |
| SCHEMBL6131328 | 0.81 | AKR1C3 (0.48) | AKR1C3ALDH1A1TSHRRECQLMEN1 | |
| SCHEMBL20585548 | 0.79 | AKR1C3 (0.50) | AKR1C3ALDH1A1TSHRRECQLMEN1 | |
| SCHEMBL27590408 | 0.79 | MEN1 (0.51) | AKR1C3ALDH1A1TSHRRECQLMEN1 | |
| SCHEMBL20585547 | 0.79 | AKR1C3 (0.50) | AKR1C3ALDH1A1TSHRRECQLMEN1 | |
| SCHEMBL4729744 | 0.77 | AKR1C3 (0.62) | AKR1C3ALDH1A1TSHRRECQLMEN1 | |
| SCHEMBL28903785 | 0.74 | ALDH1A1 (0.52) | AKR1C3ALDH1A1TSHRRECQLMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0873123-A4 | INHIBITORS OF PROTEIN ISOPRENYL TRANSFERASES | UNIV PITTSBURGH (US) | 1999-02-03 | — | — | EP | disclosed |
| EP-0873123-A1 | INHIBITORS OF PROTEIN ISOPRENYL TRANSFERASES | UNIVERSITY OF PITTSBURGH (US) | 1998-10-28 | — | — | EP | disclosed |
| WO-1997017070-A1 | INHIBITORS OF PROTEIN ISOPRENYL TRANSFERASES | UNIVERSITY OF PITTSBURGH (US) | 1997-05-15 | — | — | WO | disclosed |