Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 8/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.53 |
| ▸ | GAA | P10253 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 3/20 | 0.48 |
| ▸ | LMNA | P02545 | 3/20 | 0.48 |
| ▸ | MEN1 | O00255 | 4/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 7/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.45 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.45 |
| ▸ | CASP3 | P42574 | 1/20 | 0.43 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8509186 | 1.00 | RAB9A (0.53) | RAB9ASMN1; SMN2GAAMAPTLMNA | |
| SCHEMBL29350028 | 0.85 | RAB9A (0.54) | RAB9ASMN1; SMN2GAAMAPTLMNA | |
| SCHEMBL288854 | 0.85 | RAB9A (0.54) | RAB9ASMN1; SMN2GAAMAPTLMNA | |
| SCHEMBL29478375 | 0.85 | RAB9A (0.54) | RAB9ASMN1; SMN2GAAMAPTLMNA | |
| SCHEMBL43518 | 0.85 | RAB9A (0.54) | RAB9ASMN1; SMN2GAAMAPTLMNA | |
| SCHEMBL43517 | 0.85 | RAB9A (0.54) | RAB9ASMN1; SMN2GAAMAPTLMNA | |
| Hydrochloric Acid SCHEMBL2351803 | 0.83 | RAB9A (0.53) | RAB9ASMN1; SMN2GAAMAPTLMNA | |
| Hydrochloric Acid SCHEMBL2351807 | 0.83 | RAB9A (0.53) | RAB9ASMN1; SMN2GAAMAPTLMNA | |
| SCHEMBL4299166 | 0.83 | RAB9A (0.47) | RAB9ASMN1; SMN2GAAMAPTLMNA | |
| SCHEMBL454293 | 0.82 | RECQL (0.58) | RAB9ASMN1; SMN2GAAMAPTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5955435-A | Peptidyl compounds having MMP and TNF inhibitory activity | DARWIN DISCOVERY LIMITED (GB) | 1999-09-21 | — | — | US | disclosed |
| EP-0925281-A1 | PEPTIDYL COMPOUNDS HAVING MMP AND TNF INHIBITORY ACTIVITY | Darwin Discovery Limited (GB) | 1999-06-30 | — | — | EP | disclosed |
| WO-1998006696-A1 | PEPTIDYL COMPOUNDS HAVING MMP AND TNF INHIBITORY ACTIVITY | DARWIN DISCOVERY LIMITED (GB) | 1998-02-19 | — | — | WO | disclosed |