SCHEMBL8509902

SCHEMBL8509902

CC#CCc1c[nH]c(=O)[nH]c1=S

nearest known ligand 0.35

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
ATAD2 Q6PL18 1/20 0.33
DPYD Q12882 2/20 0.31
MMP2 P08253 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3485396 0.82 ATAD2 (0.44) ATAD2DPYD
SCHEMBL8508881 0.76 KMT2A (0.48)
SCHEMBL21345580 0.72 GAA (0.39) ATAD2DPYDMMP2
SCHEMBL766521 0.71 ATAD2 (0.35) ATAD2
SCHEMBL4373860 0.69 DPYD (0.41) ATAD2DPYDMMP2
SCHEMBL8509899 0.66 DPYD (0.38) ATAD2DPYDMMP2
SCHEMBL65835 0.65
SCHEMBL21345256 0.64 DPYD (0.64) ATAD2DPYDMMP2
SCHEMBL22571173 0.64 ATAD2 (0.39) ATAD2DPYDMMP2
SCHEMBL2826221 0.64

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0923596-A2 LIPOPHILIC OLIGONUCLEOTIDE ANALOGS GILEAD SCIENCES, INC. (US) 1999-06-23 EP disclosed
WO-1998004575-A2 LIPOPHILIC OLIGONUCLEOTIDE ANALOGS GILEAD SCIENCES, INC. (US) 1998-02-05 WO disclosed