Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 5/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | CA2 | P00918 | 1/20 | 0.42 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.40 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.40 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | SCN1A | P35498 | 2/20 | 0.38 |
| ▸ | SCN2A | Q99250 | 2/20 | 0.38 |
| ▸ | SCN3A | Q9NY46 | 2/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | THRA | P10827 | 1/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3290028 | 0.91 | TSHR (0.50) | TSHRTDP1L3MBTL1CYP3A4MAPK1 | |
| SCHEMBL8435790 | 0.90 | TSHR (0.54) | TSHRTDP1L3MBTL1CYP3A4MAPK1 | |
| SCHEMBL8512469 | 0.88 | TSHR (0.51) | TSHRTDP1L3MBTL1CYP3A4MAPK1 | |
| SCHEMBL8435791 | 0.84 | ALDH1A1 (0.51) | TSHRTDP1L3MBTL1CYP3A4MAPK1 | |
| SCHEMBL30656414 | 0.84 | TSHR (0.53) | TSHRTDP1L3MBTL1CYP3A4MAPK1 | |
| SCHEMBL8512473 | 0.81 | LMNA (0.46) | TSHRTDP1L3MBTL1CYP3A4MAPK1 | |
| SCHEMBL28805247 | 0.80 | TSHR (0.46) | TSHRTDP1L3MBTL1CYP3A4MAPK1 | |
| SCHEMBL6463491 | 0.79 | TSHR (0.51) | TSHRTDP1L3MBTL1CYP3A4MAPK1 | |
| SCHEMBL28406804 | 0.78 | ALDH1A1 (0.53) | TSHRTDP1L3MBTL1CYP3A4MAPK1 | |
| SCHEMBL28087118 | 0.78 | TSHR (0.45) | TSHRTDP1L3MBTL1CYP3A4MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5730996-A | Intercalates and expoliates formed with organic pesticide compounds and compositions containing the same | AMCOL INTERNATIONAL CORPORATION (US) | 1998-03-24 | — | — | US | claimed |
| US-5906916-A | COMPOSITION COMPRISING IODIDE SALT, BUFFER, WATER SOLUBLE CELLULOSE BASED POLYMER, WATER CARRIER; EXHIBITS COLOR TRANSITION IN RESPONSE TO PEROXIDE | INTEGRATED BIOMEDICAL TECHNOLOGY INC. (US) | 1999-05-25 | — | — | US | disclosed |