SCHEMBL8512469

SCHEMBL8512469

CCCCc1ccccc1C(=O)OC(=O)c1ccccc1CCCC

nearest known ligand 0.51

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
TSHR P16473 6/20 0.51
TDP1 Q9NUW8 2/20 0.51
L3MBTL1 Q9Y468 2/20 0.51
ALDH1A1 P00352 6/20 0.50
CYP3A4 P08684 3/20 0.50
LMNA P02545 2/20 0.50
MAPK1 P28482 2/20 0.50
TP53 P04637 1/20 0.50
KMT2A Q03164 1/20 0.46
HSD17B10 Q99714 1/20 0.45
SCN1A P35498 2/20 0.45
SCN2A Q99250 2/20 0.45
SCN3A Q9NY46 2/20 0.45
LIPG Q9Y5X9 1/20 0.43
HTT P42858 1/20 0.43
THRA P10827 1/20 0.43
THRB P10828 1/20 0.43
CA2 P00918 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8435790 0.98 TSHR (0.54) TSHRTDP1L3MBTL1ALDH1A1CYP3A4
SCHEMBL30656414 0.95 TSHR (0.53) TSHRTDP1L3MBTL1ALDH1A1CYP3A4
SCHEMBL3290028 0.94 TSHR (0.50) TSHRTDP1L3MBTL1ALDH1A1CYP3A4
SCHEMBL8512473 0.92 LMNA (0.46) TSHRTDP1L3MBTL1ALDH1A1CYP3A4
SCHEMBL8435791 0.92 ALDH1A1 (0.51) TSHRTDP1L3MBTL1ALDH1A1CYP3A4
SCHEMBL6463491 0.89 TSHR (0.51) TSHRTDP1L3MBTL1ALDH1A1CYP3A4
SCHEMBL28406804 0.89 ALDH1A1 (0.53) TSHRTDP1L3MBTL1ALDH1A1CYP3A4
SCHEMBL28735848 0.89 KMT2A (0.49) TSHRTDP1L3MBTL1ALDH1A1CYP3A4
SCHEMBL8510022 0.88 TSHR (0.45) TSHRTDP1L3MBTL1ALDH1A1CYP3A4
SCHEMBL1789262 0.88 ALDH1A1 (0.66) TSHRTDP1L3MBTL1ALDH1A1CYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-111234070-B Catalyst component, catalyst system and prepolymerized catalyst for olefin polymerization, use thereof and olefin polymerization process 中国石油化工股份有限公司 2022-03-01 CN claimed
CN-111234073-B Catalyst component, catalyst system and prepolymerized catalyst for olefin polymerization, use thereof and olefin polymerization process 中国石油化工股份有限公司 2021-12-31 CN claimed
CN-111234070-A Catalyst component, catalyst system and prepolymerized catalyst for olefin polymerization, use thereof and olefin polymerization process 中国石油化工股份有限公司 2020-06-05 CN claimed
CN-111234073-A Catalyst component, catalyst system and prepolymerized catalyst for olefin polymerization, use thereof and olefin polymerization process 中国石油化工股份有限公司 2020-06-05 CN claimed
US-20200140624-A1 LIGNIN HYBRID POLYMERS OBTAINED FROM THE REACTION OF LIGNIN AND COMPATIBLE POLYMER PRECURSORS, AND STARTING COMPOSITIONS FOR FORMING LIGNIN HYBRID POLYMERS Organic Chemical, LLC 2020-05-07 US claimed
US-5929197-A Acylsuccinic acid polyesters, a process for their preparation and their use in thermosetting plastics and coatings BAYER AKTIENGESELLSCHAFT (DE) 1999-07-27 US claimed
JP-5222253-A None JP disclosed
US-20250084220-A1 LIGNIN HYBRID POLYMERS OBTAINED FROM THE REACTION OF LIGNIN AND COMPATIBLE POLYMER PRECURSORS, AND STARTING COMPOSITIONS FOR FORMING LIGNIN HYBRID POLYMERS Organic Chemical, LLC 2025-03-13 US disclosed
US-12157798-B2 Lignin hybrid polymers obtained from the reaction of lignin and compatible polymer precursors, and starting compositions for forming lignin hybrid polymers Organic Chemical, LLC (US) 2024-12-03 US disclosed
US-20240043627-A1 LIGNIN HYBRID POLYMERS OBTAINED FROM THE REACTION OF LIGNIN AND COMPATIBLE POLYMER PRECURSORS, AND STARTING COMPOSITIONS FOR FORMING LIGNIN HYBRID POLYMERS Organic Chemical, LLC 2024-02-08 US disclosed
US-11827752-B2 Lignin hybrid polymers obtained from the reaction of lignin and compatible polymer precursors, and starting compositions for forming lignin hybrid polymers Organic Chemical, LLC (US) 2023-11-28 US disclosed
US-20220389170-A1 LIGNIN HYBRID POLYMERS OBTAINED FROM THE REACTION OF LIGNIN AND COMPATIBLE POLYMER PRECURSORS, AND STARTING COMPOSITIONS FOR FORMING LIGNIN HYBRID POLYMERS Organic Chemical, LLC 2022-12-08 US disclosed
US-11434331-B2 Lignin hybrid polymers obtained from the reaction of lignin and compatible polymer precursors, and starting compositions for forming lignin hybrid polymers Organic Chemical, LLC (US) 2022-09-06 US disclosed
CN-111234070-B Catalyst component, catalyst system and prepolymerized catalyst for olefin polymerization, use thereof and olefin polymerization process 中国石油化工股份有限公司 2022-03-01 CN disclosed
CN-111234073-B Catalyst component, catalyst system and prepolymerized catalyst for olefin polymerization, use thereof and olefin polymerization process 中国石油化工股份有限公司 2021-12-31 CN disclosed
CN-111234070-A Catalyst component, catalyst system and prepolymerized catalyst for olefin polymerization, use thereof and olefin polymerization process 中国石油化工股份有限公司 2020-06-05 CN disclosed
CN-111234073-A Catalyst component, catalyst system and prepolymerized catalyst for olefin polymerization, use thereof and olefin polymerization process 中国石油化工股份有限公司 2020-06-05 CN disclosed
US-20200140624-A1 LIGNIN HYBRID POLYMERS OBTAINED FROM THE REACTION OF LIGNIN AND COMPATIBLE POLYMER PRECURSORS, AND STARTING COMPOSITIONS FOR FORMING LIGNIN HYBRID POLYMERS Organic Chemical, LLC 2020-05-07 US disclosed
CN-104250207-A Method for preparing 2-methyl-1-[4-(t-butyl)phenyl]-1-acetone INSIGHT HIGH TECHNOLOGY JIANGSU CO LTD 2014-12-31 CN disclosed
JP-H05222253-A POLYPROPYLENE-BASED RESIN COMPOSITION TOSOH CORP 1993-08-31 JP disclosed