Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1C3 | P42330 | 1/20 | 0.36 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.36 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.36 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.33 |
| ▸ | AMY1A | P0DUB6 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 3/20 | 0.32 |
| ▸ | THRB | P10828 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 2/20 | 0.32 |
| ▸ | F2RL3 | Q96RI0 | 1/20 | 0.32 |
| ▸ | ALPL | P05186 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1162608 | 0.82 | CYP1A1 (0.36) | MAPTTP53MEN1ALDH1A1LMNA | |
| SCHEMBL1162860 | 0.79 | ALDH1A1 (0.39) | PTGS2MAPTTHRBMEN1ALDH1A1 | |
| SCHEMBL1937701 | 0.77 | TP53 (0.36) | ADORA2AMAPTTP53 | |
| SCHEMBL1938999 | 0.74 | MEN1 (0.38) | PTGS2ADORA2AAMY1AMAPTTP53 | |
| SCHEMBL8513893 | 0.74 | CTSA (0.35) | AKR1C3AKR1C2PTGS2MAPTTHRB | |
| SCHEMBL1162286 | 0.70 | CYP1B1 (0.37) | TP53ALDH1A1CYP1A2CYP3A4CYP2C9 | |
| SCHEMBL1162395 | 0.67 | CYP1A2 (0.41) | MEN1ALDH1A1CYP1A2CYP3A4CYP2C9 | |
| SCHEMBL1559570 | 0.67 | TP53 (0.47) | MAPTTP53MEN1ALDH1A1LMNA | |
| SCHEMBL1162843 | 0.67 | PDE2A (0.38) | AKR1C3AKR1C2PTGS2MEN1ALDH1A1 | |
| SCHEMBL1162305 | 0.66 | CYP1A2 (0.34) | MEN1ALDH1A1CYP1A2CYP3A4CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120135995-A1 | FUNGICIDAL DIPHENYL-SUBSTITUTED PYRIDAZINES | E.I. DUPONT DE NEMOURS AND COMPANY (US) | 2012-05-31 | — | — | US | claimed |
| EP-2462120-A1 | FUNGICIDAL DIPHENYL-SUBSTITUTED PYRIDAZINES | E. I. du Pont de Nemours and Company (US) | 2012-06-13 | — | — | EP | disclosed |
| US-20120135995-A1 | FUNGICIDAL DIPHENYL-SUBSTITUTED PYRIDAZINES | E.I. DUPONT DE NEMOURS AND COMPANY (US) | 2012-05-31 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120135995-A1 | FUNGICIDAL DIPHENYL-SUBSTITUTED PYRIDAZINES | PNPO, CYP1B1, PRXL2A | AKR1C3 103/4885AKR1C2 735/4885PTGS2 1491/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.