Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE known ✓ | P22303 | 1/20 | 0.33 |
| ▸ | BCHE | P06276 | 1/20 | 0.33 |
| ▸ | PARP1 | P09874 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL8512931 | 0.83 | BCHE (0.31) | BCHEACHE | |
| Hydrochloric Acid SCHEMBL7548715 | 0.78 | GPR3 (0.33) | — | |
| Hydrochloric Acid SCHEMBL8511285 | 0.74 | BCHE (0.34) | BCHEACHE | |
| Hydrochloric Acid SCHEMBL8513312 | 0.74 | BCHE (0.30) | BCHEACHE | |
| Hydrochloric Acid SCHEMBL7553157 | 0.65 | NR3C1 (0.36) | ACHE | |
| Hydrochloric Acid SCHEMBL7553756 | 0.64 | GPR3 (0.31) | — | |
| Hydrochloric Acid SCHEMBL2860029 | 0.64 | GPR3 (0.31) | — | |
| Hydrochloric Acid SCHEMBL1116197 | 0.63 | GPR3 (0.32) | — | |
| Hydrochloric Acid SCHEMBL4890087 | 0.63 | GPR3 (0.32) | — | |
| Hydrochloric Acid SCHEMBL5089860 | 0.63 | GPR3 (0.32) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2570472-A1 | LUBRICATING OIL COMPOSITION | Mitsui Chemicals, Inc. (JP) | 2013-03-20 | — | — | EP | disclosed |
| US-20120135903-A1 | LUBRICATING OIL COMPOSITION | MITSUI CHEMICALS, INC. | 2012-05-31 | — | — | US | disclosed |