Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4B | Q07343 | 18/20 | 0.71 |
| ▸ | PDE4A | P27815 | 14/20 | 0.71 |
| ▸ | PDE4C | Q08493 | 13/20 | 0.71 |
| ▸ | PDE4D | Q08499 | 13/20 | 0.71 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7181002 | 0.87 | PDE4B (0.82) | PDE4BPDE4APDE4CPDE4D | |
| SCHEMBL7864287 | 0.85 | PDE4B (0.75) | PDE4BPDE4APDE4CPDE4D | |
| SCHEMBL7423821 | 0.83 | PDE4B (1.00) | PDE4BPDE4APDE4CPDE4D | |
| SCHEMBL7378466 | 0.80 | PDE4B (0.69) | PDE4BPDE4APDE4CPDE4D | |
| SCHEMBL7412995 | 0.80 | PDE4A (0.69) | PDE4BPDE4APDE4CPDE4D | |
| SCHEMBL7359794 | 0.80 | PDE4A (0.71) | PDE4BPDE4APDE4CPDE4D | |
| SCHEMBL8475654 | 0.80 | PDE4A (0.71) | PDE4BPDE4APDE4CPDE4D | |
| SCHEMBL7362543 | 0.79 | PDE4B (0.69) | PDE4BPDE4APDE4CPDE4D | |
| SCHEMBL7380495 | 0.78 | PDE4A (0.44) | PDE4BPDE4APDE4CPDE4D | |
| SCHEMBL6351319 | 0.76 | PDE4B (0.59) | PDE4BPDE4APDE4CPDE4D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5861421-A | 4,4-(disubstituted) cyclohexan-1-one monomers and related compounds | SMITHKLINE BEECHAM CORPORATION (US) | 1999-01-19 | — | — | US | disclosed |