Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4A | P27815 | 20/20 | 0.44 |
| ▸ | PDE4B | Q07343 | 20/20 | 0.44 |
| ▸ | PDE4C | Q08493 | 20/20 | 0.44 |
| ▸ | PDE4D | Q08499 | 20/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8510408 | 0.78 | PDE4B (0.71) | PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL7412995 | 0.76 | PDE4A (0.69) | PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL8508309 | 0.72 | PDE4A (0.46) | PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL7378466 | 0.72 | PDE4B (0.69) | PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL7409795 | 0.69 | PDE4A (0.52) | PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL4940189 | 0.69 | PDE4A (0.55) | PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL8509453 | 0.69 | PDE4A (0.45) | PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL7413457 | 0.69 | PDE4A (0.47) | PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL7445077 | 0.69 | PDE4A (0.61) | PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL7599286 | 0.68 | PDE4A (0.49) | PDE4APDE4BPDE4CPDE4D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0800393-A4 | 4,4-(DISUBSTITUTED)CYCLOHEXAN-1-ONE MONOMERS AND RELATED COMPOUNDS | SMITHKLINE BEECHAM CORP (US) | 1998-05-06 | — | — | EP | disclosed |
| EP-0800393-A1 | 4,4-(DISUBSTITUTED)CYCLOHEXAN-1-ONE MONOMERS AND RELATED COMPOUNDS | SMITHKLINE BEECHAM CORPORATION (US) | 1997-10-15 | — | — | EP | disclosed |
| WO-1996019995-A1 | 4,4-(DISUBSTITUTED)CYCLOHEXAN-1-ONE MONOMERS AND RELATED COMPOUNDS | SMITHKLINE BEECHAM CORPORATION (US) | 1996-07-04 | — | — | WO | disclosed |