Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8511270 | 0.82 | SIGMAR1 (0.59) | SIGMAR1 | |
| SCHEMBL9882925 | 0.81 | KDM4E (0.52) | SIGMAR1 | |
| SCHEMBL9882914 | 0.81 | MPO (0.52) | SIGMAR1 | |
| Hydrochloric Acid SCHEMBL8510696 | 0.81 | SIGMAR1 (0.58) | SIGMAR1 | |
| SCHEMBL8514118 | 0.80 | SIGMAR1 (0.51) | SIGMAR1 | |
| Hydrochloric Acid SCHEMBL8514187 | 0.80 | KDM4E (0.51) | SIGMAR1 | |
| Hydrochloric Acid SCHEMBL8513686 | 0.80 | MPO (0.51) | SIGMAR1 | |
| SCHEMBL9882928 | 0.75 | SIGMAR1 (0.46) | SIGMAR1 | |
| Hydrochloric Acid SCHEMBL8514832 | 0.74 | SIGMAR1 (0.45) | SIGMAR1 | |
| SCHEMBL8511921 | 0.74 | CA12 (0.61) | SIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20130296346-A1 | DIPHENYL-AMINE DERIVATIVES: USES, PROCESS OF SYNTHESIS AND PHARMACEUTICAL COMPOSITIONS | FAES FARMA, S.A. (ES) | 2013-11-07 | — | — | US | claimed |
| EP-2642987-A1 | DIPHENYL-AMINE DERIVATIVES: USES, PROCESS OF SYNTHESIS AND PHARMACEUTICAL COMPOSITIONS | Faes Farma, S.A. (ES) | 2013-10-02 | — | — | EP | claimed |
| EP-2465498-A1 | Diphenyl-amine derivatives: uses, process of synthesis and pharmaceutical compositions | FAES FARMA, S.A. (ES) | 2012-06-20 | — | — | EP | claimed |
| WO-2012069442-A1 | DIPHENYL-AMINE DERIVATIVES: USES, PROCESS OF SYNTHESIS AND PHARMACEUTICAL COMPOSITIONS | FAES FARMA, S.A. (ES) | 2012-05-31 | — | — | WO | claimed |
| US-20130296346-A1 | DIPHENYL-AMINE DERIVATIVES: USES, PROCESS OF SYNTHESIS AND PHARMACEUTICAL COMPOSITIONS | FAES FARMA, S.A. (ES) | 2013-11-07 | — | — | US | disclosed |
| EP-2642987-A1 | DIPHENYL-AMINE DERIVATIVES: USES, PROCESS OF SYNTHESIS AND PHARMACEUTICAL COMPOSITIONS | Faes Farma, S.A. (ES) | 2013-10-02 | — | — | EP | disclosed |
| EP-2465498-A1 | Diphenyl-amine derivatives: uses, process of synthesis and pharmaceutical compositions | FAES FARMA, S.A. (ES) | 2012-06-20 | — | — | EP | disclosed |
| WO-2012069442-A1 | DIPHENYL-AMINE DERIVATIVES: USES, PROCESS OF SYNTHESIS AND PHARMACEUTICAL COMPOSITIONS | FAES FARMA, S.A. (ES) | 2012-05-31 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130296346-A1 | DIPHENYL-AMINE DERIVATIVES: USES, PROCESS OF SYNTHESIS AND PHARMACEUTICAL COMPOSITIONS | CYP2D6, DDC, PAH | SIGMAR1 1329/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.