SCHEMBL8510441

SCHEMBL8510441

COCCC1CNCCO1

nearest known ligand 0.45

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
ADRA2C P18825 1/20 0.45
SLC6A2 P23975 12/20 0.42
SLC6A4 P31645 11/20 0.42
SLC6A3 Q01959 8/20 0.42
HTR2A P28223 4/20 0.42
HTR2B P41595 2/20 0.42
ADRB2 P07550 1/20 0.42
HTR1A P08908 1/20 0.42
ADRA1A P35348 1/20 0.42
CHEK1 O14757 1/20 0.34
HRH1 P35367 1/20 0.34
OPRD1 P41143 1/20 0.34
OPRK1 P41145 1/20 0.34
HTR3A P46098 1/20 0.34
EPHA2 P29317 1/20 0.33
MKNK1 Q9BUB5 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL597741 0.90 ADRA2C (0.41) ADRA2CSLC6A2SLC6A4SLC6A3HTR2A
SCHEMBL599223 0.90 ADRA2C (0.41) ADRA2CSLC6A2SLC6A4SLC6A3HTR2A
SCHEMBL950714 0.87 ADRA2C (0.40) ADRA2CSLC6A2SLC6A4SLC6A3HTR2A
SCHEMBL27767545 0.86 ADRA2C (0.41) ADRA2CSLC6A2SLC6A4SLC6A3HTR2A
SCHEMBL6008849 0.84 SLC6A2 (0.41) ADRA2CSLC6A2SLC6A4SLC6A3HTR2A
SCHEMBL14889216 0.83 ADRA2C (0.40) ADRA2CSLC6A2SLC6A4SLC6A3HTR2A
SCHEMBL10330624 0.81 SLC6A2 (0.47) ADRA2CSLC6A2SLC6A4SLC6A3HTR2A
SCHEMBL1746181 0.81 SLC6A2 (0.42) ADRA2CSLC6A2SLC6A4SLC6A3HTR2A
SCHEMBL13745152 0.81 SLC6A2 (0.39) ADRA2CSLC6A2SLC6A4SLC6A3HTR2A
SCHEMBL14275280 0.80 SLC6A4 (0.39) ADRA2CSLC6A2SLC6A4SLC6A3HTR2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109456704-B Metal Chemical Mechanical Planarization (CMP) compositions and methods thereof 弗萨姆材料美国有限责任公司 2021-08-27 CN disclosed
US-10920106-B2 Metal chemical mechanical planarization (CMP) composition and methods therefore VERSUM MATERIALS US, LLC (US) 2021-02-16 US disclosed
US-20200032107-A1 Metal Chemical Mechanical Planarization (CMP) Composition And Methods Therefore VERSUM MATERIALS US, LLC (US) 2020-01-30 US disclosed
US-10465096-B2 Metal chemical mechanical planarization (CMP) composition and methods therefore VERSUM MATERIALS US, LLC (US) 2019-11-05 US disclosed
CN-109456704-A Metal chemical mechanical planarization (CMP) compositions and methods thereof 弗萨姆材料美国有限责任公司 2019-03-12 CN disclosed
CN-105037382-B Bergenin analog derivative and its preparation method and application 中国药科大学 2017-08-25 CN disclosed
CN-105037382-A Bergenin derivatives, and preparation method and application thereof UNIV CHINA PHARMA 2015-11-11 CN disclosed
EP-1885187-B1 METHODS FOR TREATING DRUG RESISTANT CANCER NOVARTIS AG (CH) 2013-09-25 EP disclosed
WO-2013000924-A1 1-ARYL-4-METHYL-[1,2,4]TRIAZOLO[4,3-a]QUINOXALINE DERIVATIVES JANSSEN PHARMACEUTICA NV (BE) 2013-01-03 WO disclosed
CN-102694205-A Electrolyte solvent and electrolyte solution for lithium oxysalt anode active substance, and lithium ion secondary cell SHOEI CHEMICAL IND CO 2012-09-26 CN disclosed
EP-0935625-A1 RIGID POLYURETHANE FOAMS IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1999-08-18 EP disclosed
WO-1998020059-A1 RIGID POLYURETHANE FOAMS IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1998-05-14 WO disclosed