SCHEMBL8510683

SCHEMBL8510683

C=CCCC(c1ccccc1)c1ccccc1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HRH1 P35367 7/20 0.50
HTR2A P28223 7/20 0.46
CYP2C19 P33261 2/20 0.44
TAAR1 Q96RJ0 1/20 0.42
KCNH2 Q12809 3/20 0.41
CYP3A4 P08684 2/20 0.41
CYP2D6 P10635 2/20 0.41
CHRM2 P08172 1/20 0.41
HTR1A P08908 1/20 0.41
ADRA2A P08913 1/20 0.41
ADORA3 P0DMS8 1/20 0.41
CHRM1 P11229 1/20 0.41
SMPD1 P17405 1/20 0.41
DRD1 P21728 1/20 0.41
TBXA2R P21731 1/20 0.41
SLC6A2 P23975 1/20 0.41
SLC6A4 P31645 1/20 0.41
ADRA1A P35348 1/20 0.41
OPRM1 P35372 1/20 0.41
DRD3 P35462 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9074491 0.86 HRH1 (0.54) HRH1HTR2ACYP2C19TAAR1KCNH2
SCHEMBL4762903 0.84 CYP2C19 (0.42) HRH1HTR2ACYP2C19TAAR1LMNA
SCHEMBL8775873 0.84 TBXAS1 (0.52) CYP2C19KCNH2CYP3A4CYP2D6SLC6A2
SCHEMBL8837064 0.83 HRH1 (0.50) HRH1HTR2ACYP2C19ALDH1A1SIGMAR1
SCHEMBL16685070 0.80 CNR1 (0.40) CYP2C19TAAR1CYP3A4CYP2D6CHRM2
SCHEMBL8067055 0.80 CYP2C19 (0.44) HRH1HTR2ACYP2C19TAAR1
SCHEMBL7484922 0.80 RIPK1 (0.55) CYP2C19LMNA
SCHEMBL8050506 0.80 CYP2C19 (0.44) HRH1HTR2ACYP2C19TAAR1
SCHEMBL4633732 0.80 CYP2C19 (0.40) HRH1HTR2ACYP2C19TAAR1LMNA
SCHEMBL4633729 0.80 CYP2C19 (0.40) HRH1HTR2ACYP2C19TAAR1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-2191639-A None JP disclosed
CN-116634871-A Pesticidal compounds and compositions, methods of use and methods of preparation thereof 阿达玛马克西姆有限公司 2023-08-22 CN disclosed
EP-2642987-A1 DIPHENYL-AMINE DERIVATIVES: USES, PROCESS OF SYNTHESIS AND PHARMACEUTICAL COMPOSITIONS Faes Farma, S.A. (ES) 2013-10-02 EP disclosed
WO-2012069442-A1 DIPHENYL-AMINE DERIVATIVES: USES, PROCESS OF SYNTHESIS AND PHARMACEUTICAL COMPOSITIONS FAES FARMA, S.A. (ES) 2012-05-31 WO disclosed
JP-H02191639-A UNSATURATED POLYESTER RESIN MOLDING COMPOUND AND MOLDED PRODUCT THEREOF TAKEDA CHEM IND LTD 1990-07-27 JP disclosed