SCHEMBL8511440

SCHEMBL8511440

OC/C=C/C=C/CCc1cccnc1

nearest known ligand 0.49

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
CHRNA7 P36544 2/20 0.49
GPR52 Q9Y2T5 1/20 0.48
CYP2A6 P11509 1/20 0.46
TDP1 Q9NUW8 1/20 0.45
L3MBTL1 Q9Y468 1/20 0.45
TBXAS1 P24557 7/20 0.44
HRH1 P35367 2/20 0.44
CYP1A2 P05177 1/20 0.42
CYP2D6 P10635 1/20 0.42
NAPRT Q6XQN6 1/20 0.42
FDPS P14324 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9608492 0.90 CHRNA7 (0.52) CHRNA7GPR52CYP2A6TDP1L3MBTL1
SCHEMBL8514456 0.83 CHRNA7 (0.49) CHRNA7GPR52CYP2A6TDP1L3MBTL1
SCHEMBL9608856 0.83 CHRNA7 (0.58) CHRNA7GPR52CYP2A6TDP1L3MBTL1
SCHEMBL8512647 0.81 GPR52 (0.57) CHRNA7GPR52TBXAS1NAPRT
SCHEMBL8512649 0.81 GPR52 (0.57) CHRNA7GPR52TBXAS1NAPRT
SCHEMBL9608746 0.81 CHRNA7 (0.50) CHRNA7GPR52CYP2A6TDP1L3MBTL1
SCHEMBL8512519 0.78 GPR52 (0.50) GPR52TDP1
SCHEMBL16653316 0.78 GPR52 (0.50) GPR52TDP1
SCHEMBL7241565 0.77 CHRNA7 (0.57) CHRNA7CYP2A6TDP1L3MBTL1TBXAS1
SCHEMBL868537 0.77 CHRNA7 (0.57) CHRNA7CYP2A6TDP1L3MBTL1TBXAS1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2012069605-A1 NOVEL E,E-DIENE COMPOUNDS AND THEIR USE AS MEDICAMENTS AND COSMETICS DR. AUGUST WOLFF GMBH & CO. KG ARZNEIMITTEL (DE) 2012-05-31 WO disclosed
WO-2012069605-A1 NOVEL E,E-DIENE COMPOUNDS AND THEIR USE AS MEDICAMENTS AND COSMETICS DR. AUGUST WOLFF GMBH & CO. KG ARZNEIMITTEL (DE) 2012-05-31 WO disclosed