Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR52 | Q9Y2T5 | 2/20 | 0.57 |
| ▸ | TBXAS1 | P24557 | 13/20 | 0.51 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.49 |
| ▸ | PTAFR | P25105 | 1/20 | 0.44 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8512647 | 1.00 | GPR52 (0.57) | GPR52TBXAS1NAPRTPTAFRCHRNA7 | |
| SCHEMBL8514458 | 0.89 | GPR52 (0.65) | GPR52TBXAS1NAPRTCHRNA7 | |
| SCHEMBL8514462 | 0.89 | GPR52 (0.65) | GPR52TBXAS1NAPRTCHRNA7 | |
| SCHEMBL10719514 | 0.85 | TBXAS1 (0.54) | GPR52TBXAS1NAPRTKDM4E | |
| SCHEMBL15546010 | 0.82 | GPR52 (0.59) | GPR52 | |
| SCHEMBL8162558 | 0.82 | GPR52 (0.59) | GPR52 | |
| SCHEMBL8513342 | 0.82 | GPR52 (0.59) | GPR52 | |
| SCHEMBL8511440 | 0.81 | CHRNA7 (0.49) | GPR52TBXAS1NAPRTCHRNA7 | |
| SCHEMBL9608827 | 0.81 | GPR52 (0.47) | GPR52TBXAS1PTAFRCHRNA7 | |
| SCHEMBL11062791 | 0.80 | TBXAS1 (0.67) | GPR52TBXAS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012069605-A1 | NOVEL E,E-DIENE COMPOUNDS AND THEIR USE AS MEDICAMENTS AND COSMETICS | DR. AUGUST WOLFF GMBH & CO. KG ARZNEIMITTEL (DE) | 2012-05-31 | — | — | WO | disclosed |