Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ANPEP | P15144 | 1/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.41 |
| ▸ | BACE1 | P56817 | 1/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.39 |
| ▸ | TAAR1 | Q96RJ0 | 4/20 | 0.38 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.38 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.38 |
| ▸ | MAOA | P21397 | 1/20 | 0.38 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21410863 | 0.76 | KDM4E (0.51) | CYP2D6KDM4EMEN1ALDH1A1LMNA | |
| SCHEMBL23211680 | 0.76 | KDM4E (0.51) | CYP2D6KDM4EMEN1ALDH1A1LMNA | |
| SCHEMBL11445306 | 0.72 | EPHX1 (0.50) | ANPEPCYP2D6ALDH1A1LMNACYP1A2 | |
| SCHEMBL9724871 | 0.70 | MME (0.57) | MEN1ALDH1A1MAPTKMT2ACPA3 | |
| SCHEMBL30826531 | 0.69 | HDAC1 (0.45) | CYP2D6KDM4EMEN1ALDH1A1LMNA | |
| SCHEMBL9066111 | 0.69 | HDAC1 (0.45) | CYP2D6KDM4EMEN1ALDH1A1LMNA | |
| SCHEMBL396451 | 0.67 | BACE1 (0.65) | CYP2D6KDM4EMEN1ALDH1A1LMNA | |
| SCHEMBL29922357 | 0.67 | BACE1 (0.65) | CYP2D6KDM4EMEN1ALDH1A1LMNA | |
| SCHEMBL22150361 | 0.66 | MAPT (0.46) | CYP2D6KDM4EMEN1ALDH1A1LMNA | |
| SCHEMBL29922761 | 0.66 | MAPT (0.46) | CYP2D6KDM4EMEN1ALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5981491-A | PEPTIDES; METALLOENZYMES; TUMOR NECROSIS FACTOR | DARWIN DISCOVERY LIMITED (GB) | 1999-11-09 | — | — | US | disclosed |