Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.54 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | SCN1A | P35498 | 1/20 | 0.44 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.44 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.41 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.41 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.40 |
| ▸ | CHRNA5 | P30532 | 1/20 | 0.40 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.40 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Benzoic Acid SCHEMBL28606122 | 0.75 | DAO (0.41) | SMN1; SMN2LMNAKMT2ASLC6A2SLC6A3 | |
| SCHEMBL20425540 | 0.75 | ALDH1A1 (0.44) | SMN1; SMN2LMNAGAAALDH1A1TSHR | |
| SCHEMBL10247167 | 0.74 | ALDH1A1 (0.44) | SMN1; SMN2TDP1LMNAMAPK1KMT2A | |
| Bromide SCHEMBL28608648 | 0.74 | ALDH1A1 (0.42) | SMN1; SMN2GAAALDH1A1TSHRCHRNB2 | |
| Benzoic Acid SCHEMBL28606180 | 0.73 | TSHR (0.39) | LMNAKMT2AALDH1A1TSHR | |
| Ammonia Solution, Strong SCHEMBL28935110 | 0.73 | ALDH1A1 (0.43) | SMN1; SMN2TDP1LMNAMAPK1KMT2A | |
| SCHEMBL137486 | 0.72 | TDP1 (0.83) | SMN1; SMN2TDP1LMNAMAPK1KMT2A | |
| Benzoic Acid SCHEMBL28607270 | 0.72 | DAO (0.44) | SMN1; SMN2LMNAMAPK1SLC6A2SLC6A3 | |
| SCHEMBL28239672 | 0.71 | SMN1; SMN2 (0.54) | SMN1; SMN2TDP1LMNASCN1ASCN2A | |
| SCHEMBL501862 | 0.71 | KMT2A (0.72) | SMN1; SMN2TDP1SCN1ASCN2ASCN3A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5958969-A | OSTEOPOROSIS | ELI LILLY AND COMPANY (US) | 1999-09-28 | — | — | US | disclosed |