Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.33 |
| ▸ | TACR3 | P29371 | 1/20 | 0.30 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19510937 | 0.78 | FFAR4 (0.36) | — | |
| SCHEMBL8515255 | 0.76 | FFAR4 (0.38) | — | |
| SCHEMBL8511650 | 0.74 | IKBKB (0.40) | — | |
| SCHEMBL8514006 | 0.71 | GPR119 (0.33) | HRH3 | |
| SCHEMBL8510970 | 0.71 | GPR119 (0.52) | — | |
| SCHEMBL25395289 | 0.69 | CHRNB2 (0.45) | HRH3 | |
| SCHEMBL8515035 | 0.68 | HRH3 (0.43) | HRH3 | |
| SCHEMBL8515851 | 0.67 | DGAT1 (0.49) | HRH3KCNH2 | |
| SCHEMBL13855656 | 0.66 | SCD (0.41) | KCNH2 | |
| SCHEMBL21004577 | 0.65 | EPHX2 (0.42) | HRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2643311-A1 | BICYCLIC GPR119 MODULATORS | Lupin Limited (IN) | 2013-10-02 | — | — | EP | disclosed |
| WO-2012069917-A1 | BICYCLIC GPR119 MODULATORS | LUPIN LIMITED (IN) | 2012-05-31 | — | — | WO | disclosed |