Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RBP4 | P02753 | 3/20 | 0.39 |
| ▸ | ABL1 | P00519 | 10/20 | 0.35 |
| ▸ | DYRK1A | Q13627 | 7/20 | 0.33 |
| ▸ | GSK3B | P49841 | 5/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL209593 | 0.93 | ABL1 (0.34) | RBP4ABL1DYRK1AGSK3B | |
| SCHEMBL210749 | 0.91 | ABL1 (0.35) | ABL1DYRK1AGSK3B | |
| SCHEMBL212717 | 0.91 | ABL1 (0.35) | RBP4ABL1DYRK1AGSK3B | |
| SCHEMBL212572 | 0.90 | ABL1 (0.39) | ABL1 | |
| SCHEMBL211158 | 0.86 | ABL1 (0.38) | ABL1DYRK1AGSK3B | |
| SCHEMBL211149 | 0.85 | ABL1 (0.37) | ABL1DYRK1AGSK3B | |
| SCHEMBL211453 | 0.84 | ABL1 (0.36) | ABL1DYRK1AGSK3B | |
| SCHEMBL212462 | 0.84 | MAPK1 (0.35) | ABL1DYRK1AGSK3B | |
| SCHEMBL212756 | 0.84 | NOTUM (0.37) | ABL1DYRK1AGSK3B | |
| SCHEMBL2723514 | 0.83 | ABL1 (0.34) | ABL1DYRK1AGSK3B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120135964-A1 | CERTAIN CHEMICAL ENTITIES, COMPOSITIONS, AND METHODS | QIAN XIANGPING (US) | 2012-05-31 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120135964-A1 | CERTAIN CHEMICAL ENTITIES, COMPOSITIONS, AND METHODS | MYLK, MYH2, MYH10 | RBP4 2186/4885ABL1 956/4885DYRK1A 4356/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.