Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 4/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.41 |
| ▸ | CASP1 | P29466 | 3/20 | 0.40 |
| ▸ | CASP7 | P55210 | 2/20 | 0.40 |
| ▸ | HBB | P68871 | 2/20 | 0.40 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 5/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.33 |
| ▸ | RAB9A | P51151 | 2/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 2/20 | 0.31 |
| ▸ | USP2 | O75604 | 2/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.31 |
| ▸ | MAPT | P10636 | 2/20 | 0.31 |
| ▸ | HTT | P42858 | 2/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9750621 | 0.75 | TERT (0.43) | ATMCYP3A4ALDH1A1HSD17B10CASP1 | |
| SCHEMBL9332398 | 0.75 | CYP3A4 (0.41) | ATMCYP3A4ALDH1A1HSD17B10CASP1 | |
| SCHEMBL13806417 | 0.75 | ATM (0.50) | ATMALDH1A1MEN1KMT2ARAB9A | |
| SCHEMBL1285478 | 0.75 | ATM (0.50) | ATMALDH1A1MEN1KMT2ARAB9A | |
| SCHEMBL2796407 | 0.75 | ATM (0.50) | ATMALDH1A1TDP1MEN1KMT2A | |
| SCHEMBL25413825 | 0.75 | ATM (0.50) | ATMALDH1A1HSD17B10MEN1KMT2A | |
| SCHEMBL1394239 | 0.75 | ATM (0.50) | ATMALDH1A1HSD17B10MEN1KMT2A | |
| SCHEMBL8512795 | 0.75 | ATM (0.50) | ATMALDH1A1MEN1KMT2ARAB9A | |
| SCHEMBL4164409 | 0.75 | ATM (0.50) | ATMALDH1A1MEN1KMT2ARAB9A | |
| SCHEMBL2008748 | 0.73 | PARP1 (0.50) | ATMALDH1A1MEN1KMT2ARAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11820973-B2 | Methods and system for interfering with viability of bacteria and related compounds and compositions | CALIFORNIA INSTITUTE OF TECHNOLOGY (US) | 2023-11-21 | — | — | US | disclosed |
| US-10578624-B2 | Determination of glycosaminoglycan levels by mass spectrometry | SHIRE HUMAN GENETIC THERAPIES, INC. (US) | 2020-03-03 | — | — | US | disclosed |
| CN-107003324-B | Determination of glycosaminoglycan levels by mass spectrometry | 夏尔人类遗传性治疗公司 | 2019-09-24 | — | — | CN | disclosed |
| US-20170350900-A1 | DETERMINATION OF GLYCOSAMINOGLYCAN LEVELS BY MASS SPECTROMETRY | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2017-12-07 | — | — | US | disclosed |
| EP-3218722-A1 | DETERMINATION OF GLYCOSAMINOGLYCAN LEVELS BY MASS SPECTROMETRY | Shire Human Genetic Therapies, Inc. (US) | 2017-09-20 | — | — | EP | disclosed |
| CN-107003324-A | Determination of glycosaminoglycan levels by mass spectrometry | 夏尔人类遗传性治疗公司 | 2017-08-01 | — | — | CN | disclosed |
| WO-2016077775-A1 | DETERMINATION OF GLYCOSAMINOGLYCAN LEVELS BY MASS SPECTROMETRY | SHIRE HUMAN GENETIC THERAPIES, INC. (US) | 2016-05-19 | — | — | WO | disclosed |
| EP-1011677-A4 | 4-ARYL-3-AMINOQUINOLINE-2-ONE DERIVATIVES AS POTASSIUM CHANNEL MODULATORS | BRISTOL MYERS SQUIBB CO (US) | 2002-03-20 | — | — | EP | disclosed |
| EP-1011677-A1 | 4-ARYL-3-AMINOQUINOLINE-2-ONE DERIVATIVES AS POTASSIUM CHANNEL MODULATORS | Bristol-Myers Squibb Company (US) | 2000-06-28 | — | — | EP | disclosed |
| US-5972961-A | ANTIISCHEMIC AGENTS; ANTICONVULSANTS; HEADACHES; SEXUAL DISORDERS | BRISTOL-MYERS SQUIBB COMPANY (US) | 1999-10-26 | — | — | US | disclosed |
| WO-1999009983-A1 | 4-ARYL-3-AMINOQUINOLINE-2-ONE DERIVATIVES AS POTASSIUM CHANNEL MODULATORS | BRISTOL-MYERS SQUIBB COMPANY (US) | 1999-03-04 | — | — | WO | disclosed |