Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 3/20 | 0.50 |
| ▸ | MEN1 | O00255 | 4/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | CASP6 | P55212 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | NQO2 | P16083 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | MPI | P34949 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | ESR1 | P03372 | 3/20 | 0.32 |
| ▸ | ESR2 | Q92731 | 3/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | PARP1 | P09874 | 1/20 | 0.31 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.31 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1285478 | 0.75 | ATM (0.50) | ATMMEN1KMT2APOLBCASP6 | |
| SCHEMBL13806417 | 0.75 | ATM (0.50) | ATMMEN1KMT2APOLBCASP6 | |
| SCHEMBL8512795 | 0.75 | ATM (0.50) | ATMMEN1KMT2APOLBCASP6 | |
| SCHEMBL1394239 | 0.75 | ATM (0.50) | ATMMEN1KMT2APOLBCASP6 | |
| SCHEMBL2796407 | 0.75 | ATM (0.50) | ATMMEN1KMT2ACYP1A2KDM4E | |
| SCHEMBL25413825 | 0.75 | ATM (0.50) | ATMMEN1KMT2APOLBCASP6 | |
| SCHEMBL7479947 | 0.75 | ATM (0.50) | ATMMEN1KMT2APOLBCASP6 | |
| SCHEMBL21988773 | 0.75 | ERN1 (0.34) | MEN1KMT2APOLBCASP6KDM4E | |
| SCHEMBL3264399 | 0.73 | MEN1 (0.47) | ATMMEN1KMT2APOLBCASP6 | |
| SCHEMBL2008748 | 0.73 | PARP1 (0.50) | ATMMEN1KMT2AKDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 48 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250163088-A1 | HALF-SANDWICH TRANSITION METAL COMPLEXES AND USES THEREOF | DEBRECENI EGYETEM (HU) | 2025-05-22 | — | — | US | disclosed |
| EP-4463230-A1 | HALF-SANDWICH TRANSITION METAL COMPLEXES AND USES THEREOF | Debreceni Egyetem (HU) | 2024-11-20 | — | — | EP | disclosed |
| US-11987589-B2 | Heterocyclic flavone derivatives, compositions, and methods related thereto | EMORY UNIVERSITY (US) | 2024-05-21 | — | — | US | disclosed |
| EP-4344743-A2 | HETEROCYCLIC FLAVONE DERIVATIVES, COMPOSITIONS, AND METHODS RELATED THERETO | Emory University (US) | 2024-04-03 | — | — | EP | disclosed |
| EP-3833343-B1 | HETEROCYCLIC FLAVONE DERIVATIVES, COMPOSITIONS, AND METHODS RELATED THERETO | UNIV EMORY (US) | 2024-02-21 | — | — | EP | disclosed |
| WO-2023041947-A1 | HALF-SANDWICH TRANSITION METAL COMPLEXES AND USES THEREOF | DEBRECENI EGYETEM (HU) | 2023-03-23 | — | — | WO | disclosed |
| US-20210292335-A1 | Heterocyclic Flavone Derivatives, Compositions, and Methods Related Thereto | EMORY UNIVERSITY | 2021-09-23 | — | — | US | disclosed |
| CN-107868071-B | 7, 8-dihydroxyflavone and 7, 8-substituted flavone derivatives, compositions, and methods related thereto | 爱默蕾大学 | 2021-07-20 | — | — | CN | disclosed |
| EP-3833343-A1 | HETEROCYCLIC FLAVONE DERIVATIVES, COMPOSITIONS, AND METHODS RELATED THERETO | Emory University (US) | 2021-06-16 | — | — | EP | disclosed |
| EP-3369730-B1 | 7,8-DIHYDOXYFLAVONE AND 7,8-SUBSTITUTED FLAVONE DERIVATIVES, COMPOSITIONS, AND METHODS RELATED THERETO | UNIV EMORY (US) | 2020-08-05 | — | — | EP | disclosed |
| EP-0942723-B1 | 4-ARYL-3-HYDROXYQUINOLIN-2-ONE DERIVATIVES AS ION CHANNEL MODULATORS | BRISTOL MYERS SQUIBB CO (US) | 2004-01-21 | — | — | EP | disclosed |
| EP-0942723-A4 | 4-ARYL-3-HYDROXYQUINOLIN-2-ONE DERIVATIVES AS ION CHANNEL MODULATORS | BRISTOL MYERS SQUIBB CO (US) | 2002-05-15 | — | — | EP | disclosed |
| EP-1011677-A4 | 4-ARYL-3-AMINOQUINOLINE-2-ONE DERIVATIVES AS POTASSIUM CHANNEL MODULATORS | BRISTOL MYERS SQUIBB CO (US) | 2002-03-20 | — | — | EP | disclosed |
| EP-1011677-A1 | 4-ARYL-3-AMINOQUINOLINE-2-ONE DERIVATIVES AS POTASSIUM CHANNEL MODULATORS | Bristol-Myers Squibb Company (US) | 2000-06-28 | — | — | EP | disclosed |
| US-5972961-A | ANTIISCHEMIC AGENTS; ANTICONVULSANTS; HEADACHES; SEXUAL DISORDERS | BRISTOL-MYERS SQUIBB COMPANY (US) | 1999-10-26 | — | — | US | disclosed |
| EP-0942723-A1 | 4-ARYL-3-HYDROXYQUINOLIN-2-ONE DERIVATIVES AS ION CHANNEL MODULATORS | Bristol-Myers Squibb Company (US) | 1999-09-22 | — | — | EP | disclosed |
| US-5922735-A | CALCIUM-ACTIVATED POTASSIUM CHANNELS AND ARE USEFUL TREATING THE DISORDER RESPONSIVE TO THE OPENING OF THE POTASSIUM CHANNELS SUCH AS ISCHEMIA, CONVULSIONS, ASTHMA, IRRITABLE BOWEL SYNDROME, MIGRAINE, TRAUMATIC BRAIN INJURY | BRISTOL-MYERS SQUIBB COMPANY (US) | 1999-07-13 | — | — | US | disclosed |
| US-5892045-A | 4-aryl-3-hydroxyquinolin-2-one derivatives as ion channel modulators | BRISTOL-MYERS SQUIBB COMPANY (US) | 1999-04-06 | — | — | US | disclosed |
| WO-1999009983-A1 | 4-ARYL-3-AMINOQUINOLINE-2-ONE DERIVATIVES AS POTASSIUM CHANNEL MODULATORS | BRISTOL-MYERS SQUIBB COMPANY (US) | 1999-03-04 | — | — | WO | disclosed |
| WO-1998023273-A1 | 4-ARYL-3-HYDROXYQUINOLIN-2-ONE DERIVATIVES AS ION CHANNEL MODULATORS | BRISTOL-MYERS SQUIBB COMPANY (US) | 1998-06-04 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11987589-B2 | Heterocyclic flavone derivatives, compositions, and methods related thereto | BDNF, NTRK2, RHOT2 | ATM 3615/4885MEN1 2217/4885KMT2A 588/4885 |
| US-20250163088-A1 | HALF-SANDWICH TRANSITION METAL COMPLEXES AND USES THEREOF | SLC39A3, CUTA, SLC30A6 | ATM 4191/4885MEN1 232/4885KMT2A 3061/4885 |
| US-20210292335-A1 | Heterocyclic Flavone Derivatives, Compositions, and Methods Related Thereto | BDNF, NTRK2, RHOT2 | ATM 3615/4885MEN1 2217/4885KMT2A 588/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.