Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 5/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.56 |
| ▸ | LMNA | P02545 | 4/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.56 |
| ▸ | MAPT | P10636 | 3/20 | 0.56 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.56 |
| ▸ | GAA | P10253 | 1/20 | 0.56 |
| ▸ | HPGD | P15428 | 1/20 | 0.56 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.56 |
| ▸ | NPC1 | O15118 | 1/20 | 0.53 |
| ▸ | ALOX5 | P09917 | 3/20 | 0.51 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 2/20 | 0.48 |
| ▸ | PTGES | O14684 | 1/20 | 0.48 |
| ▸ | HTR6 | P50406 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6300719 | 0.91 | ALDH1A1 (0.67) | MEN1KMT2AALDH1A1LMNAKDM4E | |
| SCHEMBL8515925 | 0.88 | ALOX5 (0.64) | MEN1KMT2AALDH1A1LMNAKDM4E | |
| SCHEMBL3555503 | 0.84 | AR (0.58) | MEN1KMT2AALDH1A1LMNAKDM4E | |
| SCHEMBL8512448 | 0.83 | KMT2A (0.50) | MEN1KMT2AALDH1A1LMNAKDM4E | |
| SCHEMBL19846945 | 0.82 | KDM4E (0.58) | MEN1KMT2AALDH1A1LMNAKDM4E | |
| SCHEMBL30482846 | 0.81 | ALDH1A1 (0.76) | MEN1KMT2AALDH1A1LMNAKDM4E | |
| SCHEMBL8512623 | 0.80 | NPC1 (0.47) | MEN1KMT2AALDH1A1LMNAKDM4E | |
| SCHEMBL22877728 | 0.80 | KDM4E (0.50) | MEN1KMT2AALDH1A1LMNAKDM4E | |
| SCHEMBL14710592 | 0.79 | MAPT (0.62) | MEN1KMT2AALDH1A1LMNAKDM4E | |
| SCHEMBL6295725 | 0.78 | CSF1R (0.71) | MEN1KMT2AALDH1A1LMNAKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012069856-A1 | ANTIMALARIAL COMPOUNDS | LIVERPOOL SCHOOL OF TROPICAL MEDICINE (GB) | 2012-05-31 | — | — | WO | claimed |
| WO-2012069856-A1 | ANTIMALARIAL COMPOUNDS | LIVERPOOL SCHOOL OF TROPICAL MEDICINE (GB) | 2012-05-31 | — | — | WO | disclosed |
| WO-2012069856-A1 | ANTIMALARIAL COMPOUNDS | LIVERPOOL SCHOOL OF TROPICAL MEDICINE (GB) | 2012-05-31 | — | — | WO | disclosed |