SCHEMBL8513159

SCHEMBL8513159

CCCC(F)(C(=O)O)C(F)(F)F

nearest known ligand 0.34

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
CES2 O00748 4/20 0.34
FAAH O00519 8/20 0.33
CES1 P23141 5/20 0.32
MEN1 O00255 2/20 0.32
CYP1A2 P05177 2/20 0.32
KMT2A Q03164 2/20 0.32
HSD17B10 Q99714 1/20 0.32
THRB P10828 2/20 0.32
FFAR3 O14843 2/20 0.32
HDAC3 O15379 1/20 0.32
HDAC1 Q13547 1/20 0.32
HDAC2 Q92769 1/20 0.32
HDAC8 Q9BY41 1/20 0.32
ALDH1A1 P00352 2/20 0.31
FDPS P14324 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6256090 0.86 CES2 (0.41) CES2FAAHCES1MEN1CYP1A2
SCHEMBL6256085 0.86 CES2 (0.41) CES2FAAHCES1MEN1CYP1A2
SCHEMBL9508964 0.86 CES2 (0.41) CES2FAAHCES1MEN1CYP1A2
SCHEMBL9512023 0.84 CES2 (0.48) CES2FAAHCES1MEN1CYP1A2
SCHEMBL6250222 0.82 CES2 (0.52) CES2FAAHCES1MEN1CYP1A2
SCHEMBL9508334 0.82 CES2 (0.52) CES2FAAHCES1MEN1CYP1A2
SCHEMBL9508938 0.82 CES2 (0.52) CES2FAAHCES1MEN1CYP1A2
SCHEMBL6251804 0.82 CES2 (0.52) CES2FAAHCES1MEN1CYP1A2
SCHEMBL9511027 0.82 CES2 (0.52) CES2FAAHCES1MEN1CYP1A2
SCHEMBL6250219 0.82 CES2 (0.52) CES2FAAHCES1MEN1CYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2643289-B1 PROCESS FOR PRODUCING PERFLUORINATED ORGANIC COMPOUNDS SOLVAY SPECIALTY POLYMERS IT (IT) 2018-01-24 EP disclosed
US-9051259-B2 Process for producing perfluorinated organic compounds SOLVAY SPECIALTY POLYMERS ITALY S.P.A. (IT) 2015-06-09 US disclosed
EP-2643289-A1 PROCESS FOR PRODUCING PERFLUORINATED ORGANIC COMPOUNDS Solvay Specialty Polymers Italy S.p.A. (IT) 2013-10-02 EP disclosed
US-20130245289-A1 Process for producing perfluorinated organic compounds SOLVAY SPECIALTY POLYMERS ITALY S.P.A. (IT) 2013-09-19 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20130245289-A1 Process for producing perfluorinated organic compounds PFAS, ADH1A, CYP2F1 CES2 31/4885FAAH 230/4885CES1 71/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.