Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APP | P05067 | 1/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | SLC6A6 | P31641 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | BLM | P54132 | 1/20 | 0.44 |
| ▸ | ENPEP | Q07075 | 1/20 | 0.39 |
| ▸ | S1PR2 | O95136 | 1/20 | 0.36 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.36 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.36 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.33 |
| ▸ | PDE4A | P27815 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL999249 | 0.86 | LMNA (0.48) | APPLMNASLC6A6CYP2C19BLM | |
| SCHEMBL28606531 | 0.82 | APP (0.46) | APPLMNASLC6A6CYP2C19BLM | |
| SCHEMBL9318719 | 0.81 | APP (0.42) | APPLMNASLC6A6CYP2C19BLM | |
| SCHEMBL27899209 | 0.80 | APP (0.44) | APPLMNASLC6A6CYP2C19BLM | |
| SCHEMBL28595839 | 0.80 | APP (0.44) | APPLMNASLC6A6CYP2C19BLM | |
| SCHEMBL1491254 | 0.78 | APP (0.52) | APPLMNASLC6A6CYP2C19BLM | |
| SCHEMBL28704557 | 0.76 | APP (0.50) | APPLMNASLC6A6CYP2C19BLM | |
| SCHEMBL10882721 | 0.76 | ENPEP (0.68) | LMNAENPEPTP53 | |
| Potassium Ion SCHEMBL8043024 | 0.76 | ENPEP (0.62) | LMNAENPEPTP53 | |
| SCHEMBL28595838 | 0.76 | APP (0.50) | APPLMNASLC6A6CYP2C19BLM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2643332-B1 | METHOD FOR BUFFERING A CHEMICAL OR BIOLOGICAL COMPOSITION | SACHEM INC (US) | 2014-10-22 | — | — | EP | disclosed |
| EP-2643332-A2 | METHOD FOR BUFFERING A CHEMICAL OR BIOLOGICAL COMPOSITION | Sachem, Inc. (US) | 2013-10-02 | — | — | EP | disclosed |
| WO-2012071102-A2 | BUFFER COMPOUNDS | SACHEM, INC. (US) | 2012-05-31 | — | — | WO | disclosed |
| CN-1993118-B | Aqueous eye drops with accelerated intraocular migration permeability | SENJU PHARMA CO | 2010-06-16 | — | — | CN | disclosed |
| CN-1993118-A | Aqueous eye drops with accelerated intraocular migration permeability | SENJU PHARMA CO (JP) | 2007-07-04 | — | — | CN | disclosed |
| US-5182213-A | Coupling a Phenylenediamine and a Naphthol | MILES INC. (US) | 1993-01-26 | — | — | US | disclosed |
| EP-0504663-A1 | Peroxidase indicator system for basic media | Bayer Corporation (US) | 1992-09-23 | — | — | EP | disclosed |