SCHEMBL999249

SCHEMBL999249

NCC(N)CCS(=O)(=O)O

nearest known ligand 0.64

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.48
SLC6A6 P31641 1/20 0.48
CYP2C19 P33261 1/20 0.48
BLM P54132 1/20 0.48
APP P05067 1/20 0.44
S1PR2 O95136 1/20 0.41
S1PR1 P21453 1/20 0.41
S1PR3 Q99500 1/20 0.41
PTGS1 P23219 1/20 0.36
PDE4A P27815 1/20 0.36
ENPEP Q07075 5/20 0.35
TP53 P04637 1/20 0.31
PMP22 Q01453 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8513182 0.86 APP (0.52) LMNASLC6A6CYP2C19BLMAPP
SCHEMBL820427 0.83 LMNA (0.52) LMNASLC6A6CYP2C19BLMAPP
SCHEMBL28914371 0.81 LMNA (0.50) LMNASLC6A6CYP2C19BLMAPP
SCHEMBL7160448 0.80 LMNA (0.42) LMNASLC6A6CYP2C19BLMAPP
SCHEMBL7639998 0.80 LMNA (0.42) LMNASLC6A6CYP2C19BLMAPP
Ec33 SCHEMBL1291100 0.78 ENPEP (0.59) LMNASLC6A6CYP2C19BLMS1PR2
SCHEMBL475492 0.78 S1PR2 (0.47) LMNASLC6A6CYP2C19BLMAPP
SCHEMBL4744742 0.78 S1PR2 (0.44) LMNASLC6A6CYP2C19BLMAPP
Ec33 SCHEMBL2310959 0.78 ENPEP (0.59) LMNASLC6A6CYP2C19BLMS1PR2
SCHEMBL28586828 0.78 APP (0.54) LMNASLC6A6CYP2C19BLMAPP

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 338 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0431386-B1 Heat-curable coating compositions BAYER AG (DE) 1994-09-28 EP claimed
JP-11035912-A None JP disclosed
US-12630666-B2 Urethane resin composition, foamed urethane sheet, and synthetic leather DIC CORPORATION (JP) 2026-05-19 US disclosed
US-12606953-B2 Urethane resin aqueous dispersion, synthetic leather, and method for producing synthetic leather DIC CORPORATION (JP) 2026-04-21 US disclosed
EP-3712203-B1 FOAMED URETHANE SHEET AND SYNTHETIC LEATHER DAINIPPON INK & CHEMICALS (JP) 2026-03-04 EP disclosed
US-12545760-B2 Urethane resin composition, film, and synthetic leather DIC CORPORATION (JP) 2026-02-10 US disclosed
US-12486439-B2 Urethane resin composition, adhesive, and synthetic leather DIC CORPORATION (JP) 2025-12-02 US disclosed
EP-4299830-B1 SYNTHETIC LEATHER DAINIPPON INK & CHEMICALS (JP) 2025-10-29 EP disclosed
EP-3666101-B1 METHOD FOR MANUFACTURING GLOVES DAINIPPON INK & CHEMICALS (JP) 2025-10-15 EP disclosed
EP-3901365-B1 URETHANE RESIN COMPOSITION, FILM AND SYNTHETIC LEATHER DAINIPPON INK & CHEMICALS (JP) 2025-10-15 EP disclosed
EP-0784097-A1 Dispersion of post-crosslinkable coating BAYER AG (DE) 1997-07-16 EP disclosed
EP-0525567-B1 Use of coatings in the preparation of water vapour permeable coatings BAYER AG (DE) 1996-09-04 EP disclosed
US-5518764-A APPLYING AN AQUEOUS BINDER DISPERSION TO A TEXTILE FABRIC BAYER AKTIENGESELLSCHAFT (DE) 1996-05-21 US disclosed
EP-0517029-B1 Process for the preparation of coating compositions for water-permeable coatings BAYER AG (DE) 1995-12-20 EP disclosed
EP-0674039-A2 Process for coating textiles BAYER AG (DE) 1995-09-27 EP disclosed
EP-0672948-A2 Photographic recording material Agfa-Gevaert AG (DE) 1995-09-20 EP disclosed
EP-0526815-B1 Process for tanning/impregnation and/or post-tanning of leather BAYER AG (DE) 1994-11-30 EP disclosed
EP-0431386-B1 Heat-curable coating compositions BAYER AG (DE) 1994-09-28 EP disclosed
EP-0595149-A1 Aqueous coating composition and its use for the preparation of water vapour-permeable coatings BAYER AG (DE) 1994-05-04 EP disclosed
EP-0517029-A2 Process for the preparation of coating compositions for water-permeable coatings BAYER AG (DE) 1992-12-09 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12545760-B2 Urethane resin composition, film, and synthetic leather PUF60, COL1A1, DEGS1 LMNA 744/4885SLC6A6 1182/4885CYP2C19 3417/4885
US-12606953-B2 Urethane resin aqueous dispersion, synthetic leather, and method for producing synthetic leather PUF60, CUTA, UBA2 LMNA 967/4885SLC6A6 593/4885CYP2C19 3853/4885
US-12630666-B2 Urethane resin composition, foamed urethane sheet, and synthetic leather DEGS1, EBP, UTS2R LMNA 526/4885SLC6A6 212/4885CYP2C19 4271/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.