Known targets — ChEMBL curated mechanism
ACHECHKACHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNB1CHRNDCHRNECHRNGHRH2OPRM1
The experimentally established mechanism targets of Bromide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL244806 | 0.95 | GAA (0.49) | GAAMAPTL3MBTL1KDM4EALDH1A1 | |
| Pivalate SCHEMBL9953929 | 0.79 | ALDH1A1 (0.53) | GAAMAPTL3MBTL1KDM4EALDH1A1 | |
| SCHEMBL17201196 | 0.76 | — | — | |
| SCHEMBL17799 | 0.76 | — | — | |
| SCHEMBL4166547 | 0.74 | — | — | |
| Hydrochloric Acid SCHEMBL7501190 | 0.74 | GAA (0.50) | GAAMAPTL3MBTL1KDM4EALDH1A1 | |
| Hydrochloric Acid SCHEMBL244808 | 0.74 | GAA (0.50) | GAAMAPTL3MBTL1KDM4EALDH1A1 | |
| SCHEMBL2643692 | 0.74 | — | — | |
| SCHEMBL244807 | 0.74 | GAA (0.50) | GAAMAPTL3MBTL1KDM4EALDH1A1 | |
| SCHEMBL453214 | 0.74 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012069601-A1 | SUBSTITUTED QUINAZOLINES AS FUNGICIDES | SYNGENTA PARTICIPATIONS AG (CH) | 2012-05-31 | — | — | WO | disclosed |