Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC7A5 | Q01650 | 2/20 | 0.50 |
| ▸ | ALPI | P09923 | 1/20 | 0.45 |
| ▸ | PKM | P14618 | 1/20 | 0.45 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.45 |
| ▸ | XIAP | P98170 | 1/20 | 0.45 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.43 |
| ▸ | TYR | P14679 | 1/20 | 0.43 |
| ▸ | FNTA | P49354 | 1/20 | 0.42 |
| ▸ | FNTB | P49356 | 1/20 | 0.42 |
| ▸ | SLC15A1 | P46059 | 2/20 | 0.41 |
| ▸ | MMP2 | P08253 | 1/20 | 0.40 |
| ▸ | BACE1 | P56817 | 2/20 | 0.40 |
| ▸ | CPA1 | P15085 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7865836 | 0.84 | SLC7A5 (0.49) | SLC7A5ALPIPKMPTGS1XIAP | |
| SCHEMBL9636558 | 0.81 | SLC7A5 (0.58) | SLC7A5ALPIPKMPTGS1XIAP | |
| SCHEMBL1422055 | 0.79 | SLC7A5 (0.64) | SLC7A5ALPIPKMPTGS1XIAP | |
| SCHEMBL17731623 | 0.79 | SLC7A5 (0.59) | SLC7A5ALPIPKMPTGS1XIAP | |
| SCHEMBL121369 | 0.78 | SLC7A5 (0.62) | SLC7A5ALPIPKMPTGS1XIAP | |
| SCHEMBL26023571 | 0.78 | SLC7A5 (0.62) | SLC7A5ALPIPKMPTGS1XIAP | |
| SCHEMBL16080193 | 0.78 | SLC7A5 (0.62) | SLC7A5ALPIPKMPTGS1XIAP | |
| SCHEMBL25982889 | 0.78 | SLC7A5 (0.62) | SLC7A5ALPIPKMPTGS1XIAP | |
| SCHEMBL630209 | 0.78 | SLC7A5 (0.62) | SLC7A5ALPIPKMPTGS1XIAP | |
| Hydrochloric Acid SCHEMBL9831417 | 0.76 | SLC7A5 (0.60) | SLC7A5ALPIPKMPTGS1XIAP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120136416-A1 | Caged Neuropeptides: modulation and measurement of synapse and signaling activity; and methods for drug evaluation, pharmaceuticals preparation and treatment | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2012-05-31 | — | — | US | disclosed |