Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC7A5 | Q01650 | 2/20 | 0.49 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.42 |
| ▸ | MMP2 | P08253 | 1/20 | 0.42 |
| ▸ | ALPI | P09923 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.41 |
| ▸ | XIAP | P98170 | 1/20 | 0.41 |
| ▸ | TYR | P14679 | 1/20 | 0.40 |
| ▸ | BACE1 | P56817 | 2/20 | 0.39 |
| ▸ | OPRD1 | P41143 | 2/20 | 0.39 |
| ▸ | OPRM1 | P35372 | 3/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Tyrosine SCHEMBL7373361 | 0.85 | SLC7A5 (0.60) | SLC7A5HDAC8MMP2ALPIPKM | |
| SCHEMBL8513737 | 0.84 | SLC7A5 (0.50) | SLC7A5HDAC8MMP2ALPIPKM | |
| SCHEMBL4587552 | 0.80 | KIF11 (0.39) | MMP2PKMPTGS1 | |
| SCHEMBL9636558 | 0.77 | SLC7A5 (0.58) | SLC7A5HDAC8ALPIPKMPTGS1 | |
| SCHEMBL16415724 | 0.77 | SLC7A5 (0.55) | SLC7A5HDAC8ALPIPKMPTGS1 | |
| SCHEMBL1067685 | 0.76 | SLC7A5 (0.56) | SLC7A5HDAC8MMP2 | |
| SCHEMBL1422055 | 0.75 | SLC7A5 (0.64) | SLC7A5HDAC8ALPIPKMPTGS1 | |
| SCHEMBL17731623 | 0.75 | SLC7A5 (0.59) | SLC7A5HDAC8ALPIPKMPTGS1 | |
| SCHEMBL28211011 | 0.75 | SLC7A5 (0.55) | SLC7A5HDAC8ALPIPKMPTGS1 | |
| SCHEMBL28211012 | 0.75 | SLC7A5 (0.55) | SLC7A5HDAC8ALPIPKMPTGS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6300495-B1 | REACTING ORGANIC AMINE SALT OF CLAVULANIC ACID WITH METAL SALT IN LIQUID MEDIUM OF FLUORINATED AND/OR CHLORINATED HYDROCARBON | SMITHKLINE BEECHAM P.L.C. (GB) | 2001-10-09 | — | — | US | disclosed |
| EP-0970087-A1 | A PROCESS FOR THE PREPARATION OF A METAL SALT OF CLAVULANIC ACID | SMITHKLINE BEECHAM PLC (GB) | 2000-01-12 | — | — | EP | disclosed |
| WO-1998045300-A1 | A PROCESS FOR THE PREPARATION OF A METAL SALT OF CLAVULANIC ACID | SMITHKLINE BEECHAM PLC (GB) | 1998-10-15 | — | — | WO | disclosed |
| EP-0804441-A1 | CLAVULANIC ACID EXTRACTION PROCESS | SMITHKLINE BEECHAM PLC (GB) | 1997-11-05 | — | — | EP | disclosed |
| WO-1996022296-A1 | CLAVULANIC ACID EXTRACTION PROCESS | SMITHKLINE BEECHAM P.L.C. (GB) | 1996-07-25 | — | — | WO | disclosed |