SCHEMBL851380

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL16302402	0.84	LATS1 (0.37)	MMP8ALDH1A1RAB9AKMT2ALATS1
	SCHEMBL879885	0.84	KMT2A (0.53)	ALDH1A1RAB9AKMT2AMAPTCYP1A2
	SCHEMBL16841790	0.79	POLB (0.49)	MMP8ALDH1A1RAB9AKMT2ALMNA
	SCHEMBL15803712	0.78	MAPT (0.47)	ALDH1A1RAB9ALMNATHRBMAPT
	SCHEMBL16302398	0.78	MAPT (0.40)	MMP8ALDH1A1RAB9AKMT2ALATS1
	SCHEMBL2986775	0.76	MAPT (0.56)	MMP8ALDH1A1RAB9ALMNAMAPT
	SCHEMBL4485170	0.73	ABCB11 (0.56)	ALDH1A1KMT2AMAPTTSHRABCB11
	SCHEMBL2945233	0.73	ALDH1A1 (0.50)	ALDH1A1KMT2ALMNATHRBMAPT
	SCHEMBL15061121	0.72	MAPT (0.43)	MMP8ALDH1A1RAB9AKMT2ALATS1
	SCHEMBL16104763	0.71	ALDH1A1 (0.39)	MMP8ALDH1A1KMT2AGPR35LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.