Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.50 |
| ▸ | TP53 | P04637 | 3/20 | 0.50 |
| ▸ | NPC1 | O15118 | 2/20 | 0.50 |
| ▸ | RAB9A | P51151 | 2/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | BRD9 | Q9H8M2 | 1/20 | 0.47 |
| ▸ | BRD7 | Q9NPI1 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 2/20 | 0.44 |
| ▸ | SQOR | Q9Y6N5 | 3/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.42 |
| ▸ | LMNA | P02545 | 5/20 | 0.42 |
| ▸ | POLB | P06746 | 3/20 | 0.42 |
| ▸ | CCR1 | P32246 | 2/20 | 0.42 |
| ▸ | CCR5 | P51681 | 2/20 | 0.42 |
| ▸ | CCR8 | P51685 | 2/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | METAP1 | P53582 | 1/20 | 0.42 |
| ▸ | BLM | P54132 | 1/20 | 0.42 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.42 |
| ▸ | DOHH | Q9BU89 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17521568 | 0.78 | SMN1; SMN2 (0.46) | SMN1; SMN2TP53NPC1RAB9AHPGD | |
| SCHEMBL31438401 | 0.78 | BRD9 (0.56) | SMN1; SMN2NPC1RAB9AHPGDBRD9 | |
| SCHEMBL17276010 | 0.78 | BRD9 (0.56) | SMN1; SMN2NPC1RAB9AHPGDBRD9 | |
| SCHEMBL29982775 | 0.78 | BTK (0.51) | SMN1; SMN2TP53NPC1RAB9AHPGD | |
| SCHEMBL30161832 | 0.78 | BTK (0.51) | SMN1; SMN2TP53NPC1RAB9AHPGD | |
| SCHEMBL17826973 | 0.77 | CCR1 (0.48) | SMN1; SMN2TP53NPC1RAB9AHPGD | |
| SCHEMBL20916320 | 0.75 | KDM4E (0.63) | SMN1; SMN2TP53NPC1RAB9AHPGD | |
| SCHEMBL29727932 | 0.75 | KDM4E (0.63) | SMN1; SMN2TP53NPC1RAB9AHPGD | |
| SCHEMBL10094726 | 0.74 | SQOR (0.43) | SMN1; SMN2TP53NPC1RAB9AHPGD | |
| SCHEMBL9007764 | 0.73 | BRD9 (0.41) | BRD9BRD7POLBCYP1A2TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9269912-B2 | Metal complex comprising a ligand having a combination of donor-acceptor substituents | SOLVAY SA (BE) | 2016-02-23 | — | — | US | disclosed |
| US-9269912-B2 | Metal complex comprising a ligand having a combination of donor-acceptor substituents | SOLVAY SA (BE) | 2016-02-23 | — | — | US | disclosed |
| US-20140005397-A1 | METAL COMPLEX COMPRISING A LIGAND HAVING A COMBINATION OF DONOR-ACCEPTOR SUBSTITUENTS | SOLVAY SA (BE) | 2014-01-02 | — | — | US | disclosed |
| EP-2643334-A1 | A METAL COMPLEX COMPRISING A LIGAND HAVING A COMBINATION OF DONOR-ACCEPTOR SUBSTITUENTS | SOLVAY SA (BE) | 2013-10-02 | — | — | EP | disclosed |
| WO-2012069170-A1 | A METAL COMPLEX COMPRISING A LIGAND HAVING A COMBINATION OF DONOR-ACCEPTOR SUBSTITUENTS | SOLVAY SA (BE) | 2012-05-31 | — | — | WO | disclosed |
| WO-2012069170-A1 | A METAL COMPLEX COMPRISING A LIGAND HAVING A COMBINATION OF DONOR-ACCEPTOR SUBSTITUENTS | SOLVAY SA (BE) | 2012-05-31 | — | — | WO | disclosed |