Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR1 | P32246 | 1/20 | 0.48 |
| ▸ | CCR8 | P51685 | 1/20 | 0.48 |
| ▸ | BRD9 | Q9H8M2 | 2/20 | 0.43 |
| ▸ | BRD7 | Q9NPI1 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 3/20 | 0.41 |
| ▸ | TP53 | P04637 | 3/20 | 0.41 |
| ▸ | RAB9A | P51151 | 3/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | CRHR1 | P34998 | 1/20 | 0.39 |
| ▸ | TGFBR1 | P36897 | 3/20 | 0.39 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.39 |
| ▸ | ERN1 | O75460 | 1/20 | 0.38 |
| ▸ | PDCD1LG2 | Q9BQ51 | 1/20 | 0.38 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9007764 | 0.80 | BRD9 (0.41) | BRD9BRD7POLBTDP1CRHR1 | |
| SCHEMBL22402292 | 0.78 | GABRA1 (0.44) | BRD9BRD7POLBTDP1TGFBR1 | |
| SCHEMBL17276010 | 0.78 | BRD9 (0.56) | BRD9BRD7NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL31438401 | 0.78 | BRD9 (0.56) | BRD9BRD7NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL18287242 | 0.77 | TDP1 (0.45) | BRD9BRD7NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL22939929 | 0.77 | CCR1 (0.48) | CCR1CCR8NPC1TP53RAB9A | |
| SCHEMBL13273322 | 0.77 | BRD9 (0.40) | BRD9BRD7NPC1TP53RAB9A | |
| SCHEMBL8514010 | 0.77 | SMN1; SMN2 (0.50) | CCR1CCR8BRD9BRD7NPC1 | |
| SCHEMBL3560406 | 0.74 | CCR1 (0.46) | CCR1CCR8NPC1TP53RAB9A | |
| SCHEMBL29687348 | 0.73 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2379535-B1 | 7-PHENOXYCHROMAN CARBOXYLIC ACID DERIVATIVES | ARRAY BIOPHARMA INC (US) | 2016-06-15 | — | — | EP | disclosed |