SCHEMBL9007764

SCHEMBL9007764

COc1ccc(-c2cccc(C(C)(C)c3cccc(-c4ccc(OC)nc4OC)n3)n2)c(OC)n1

nearest known ligand 0.41

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
BRD9 Q9H8M2 2/20 0.41
BRD7 Q9NPI1 2/20 0.41
POLB P06746 1/20 0.37
TDP1 Q9NUW8 1/20 0.37
CYP1A2 P05177 1/20 0.36
METAP2 P50579 1/20 0.36
ERN1 O75460 2/20 0.36
MAPT P10636 1/20 0.36
MAPK1 P28482 1/20 0.36
CRHR1 P34998 1/20 0.34
PLAU P00749 1/20 0.34
PDCD1LG2 Q9BQ51 6/20 0.33
CD274 Q9NZQ7 6/20 0.33
BTK Q06187 1/20 0.33
PRKAG1 P54619 1/20 0.33
PRKAA1 Q13131 1/20 0.33
PRKAB1 Q9Y478 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22402292 0.87 GABRA1 (0.44) BRD9BRD7POLBTDP1CYP1A2
SCHEMBL17826973 0.80 CCR1 (0.48) BRD9BRD7POLBTDP1CYP1A2
SCHEMBL17276010 0.74 BRD9 (0.56) BRD9BRD7POLBTDP1CYP1A2
SCHEMBL31438401 0.74 BRD9 (0.56) BRD9BRD7POLBTDP1CYP1A2
SCHEMBL18287242 0.74 TDP1 (0.45) BRD9BRD7POLBTDP1ERN1
SCHEMBL8514010 0.73 SMN1; SMN2 (0.50) BRD9BRD7POLBTDP1CYP1A2
SCHEMBL18287252 0.72 CYP1A2 (0.44) BRD9BRD7CYP1A2METAP2ERN1
SCHEMBL9906400 0.68 POLB (0.47) BRD9BRD7POLBTDP1CYP1A2
SCHEMBL13273322 0.67 BRD9 (0.40) BRD9BRD7POLBTDP1CYP1A2
SCHEMBL9007610 0.67 IDH1 (0.36)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8187729-B2 Organic electroluminescence device FUJIFILM CORPORATION (JP) 2012-05-29 US disclosed
US-8187729-B2 Organic electroluminescence device FUJIFILM CORPORATION (JP) 2012-05-29 US disclosed
US-20090072726-A1 ORGANIC ELECTROLUMINESCENCE DEVICE FUJIFILM CORPORATION (JP) 2009-03-19 US disclosed
US-20090072726-A1 ORGANIC ELECTROLUMINESCENCE DEVICE FUJIFILM CORPORATION (JP) 2009-03-19 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090072726-A1 ORGANIC ELECTROLUMINESCENCE DEVICE CLCN2, OR10J3, PUF60 BRD9 505/4885BRD7 1022/4885POLB 628/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.