Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 3/20 | 0.49 |
| ▸ | TRPM8 | Q7Z2W7 | 5/20 | 0.47 |
| ▸ | TRPA1 | O75762 | 2/20 | 0.47 |
| ▸ | TRPV1 | Q8NER1 | 4/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.35 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9951715 | 0.80 | EPHX1 (0.53) | EPHX1TRPM8TRPA1TRPV1KCNA5 | |
| SCHEMBL3274993 | 0.80 | EPHX1 (0.53) | EPHX1TRPM8TRPA1TRPV1KCNA5 | |
| SCHEMBL9951331 | 0.76 | EPHX1 (0.49) | EPHX1TRPM8TRPA1TRPV1 | |
| SCHEMBL30604482 | 0.74 | TRPM8 (0.62) | EPHX1TRPM8TRPA1TRPV1ALDH1A1 | |
| SCHEMBL1030886 | 0.73 | EPHX1 (0.53) | EPHX1TRPM8TRPA1TRPV1ALDH1A1 | |
| SCHEMBL9951257 | 0.73 | EPHX1 (0.53) | EPHX1TRPM8TRPA1TRPV1ALDH1A1 | |
| SCHEMBL8694409 | 0.71 | EPHX1 (0.61) | EPHX1TRPM8TRPA1TRPV1ALDH1A1 | |
| SCHEMBL10859205 | 0.71 | EPHX1 (0.51) | EPHX1TRPM8TRPA1TRPV1ALDH1A1 | |
| SCHEMBL851820 | 0.71 | EPHX1 (0.51) | EPHX1TRPM8TRPA1TRPV1ALDH1A1 | |
| SCHEMBL10593996 | 0.71 | EPHX1 (0.51) | EPHX1TRPM8TRPA1TRPV1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12601929-B2 | Contact lens | COOPERVISION INTERNATIONAL LIMITED (GB) | 2026-04-14 | — | — | US | claimed |
| EP-4388349-B1 | CONTACT LENS | COOPERVISION INT LTD (GB) | 2025-03-12 | — | — | EP | claimed |
| US-12153288-B2 | Contact lens | COOPERVISION INTERNATIONAL LIMITED (GB) | 2024-11-26 | — | — | US | claimed |
| US-20240264469-A1 | CONTACT LENS | COOPERVISION INTERNATIONAL LIMITED (GB) | 2024-08-08 | — | — | US | claimed |
| EP-4388349-A1 | CONTACT LENS | CooperVision International Limited (GB) | 2024-06-26 | — | — | EP | claimed |
| WO-2023209329-A1 | CONTACT LENS | COOPERVISION INTERNATIONAL LIMITED (GB) | 2023-11-02 | — | — | WO | claimed |
| US-20230350228-A1 | CONTACT LENS | COOPERVISION INTERNATIONAL LIMITED (GB) | 2023-11-02 | — | — | US | claimed |
| US-20120135057-A1 | ANTIPERSPIRANT COMPOSITIONS AND PRODUCTS HAVING A DISPERSED COOLING SENSATION AGENT AND METHODS FOR MAKING THE SAME | THE DIAL CORPORATION (US) | 2012-05-31 | — | — | US | claimed |
| US-20120134947-A1 | ANTIPERSPIRANT COMPOSITIONS AND PRODUCTS HAVING COOLING SENSATION EFFECTS AND METHODS FOR MAKING THE SAME | THE DIAL CORPORATION (US) | 2012-05-31 | — | — | US | claimed |
| US-12601929-B2 | Contact lens | COOPERVISION INTERNATIONAL LIMITED (GB) | 2026-04-14 | — | — | US | disclosed |
| WO-2025088339-A1 | CONTACT LENS WITH TRPM8 AGONIST IS RELEASABLY ADHERED TO THE POLYMERIC LENS BODY | COOPERVISION INTERNATIONAL LIMITED (GB) | 2025-05-01 | — | — | WO | disclosed |
| EP-4388349-B1 | CONTACT LENS | COOPERVISION INT LTD (GB) | 2025-03-12 | — | — | EP | disclosed |
| US-12153288-B2 | Contact lens | COOPERVISION INTERNATIONAL LIMITED (GB) | 2024-11-26 | — | — | US | disclosed |
| US-20240264469-A1 | CONTACT LENS | COOPERVISION INTERNATIONAL LIMITED (GB) | 2024-08-08 | — | — | US | disclosed |
| EP-4388349-A1 | CONTACT LENS | CooperVision International Limited (GB) | 2024-06-26 | — | — | EP | disclosed |
| WO-2023209329-A1 | CONTACT LENS | COOPERVISION INTERNATIONAL LIMITED (GB) | 2023-11-02 | — | — | WO | disclosed |
| US-20230350228-A1 | CONTACT LENS | COOPERVISION INTERNATIONAL LIMITED (GB) | 2023-11-02 | — | — | US | disclosed |
| US-20140161846-A1 | SUNSCREEN WITH COOLING AGENT | THE DIAL CORPORATION (US) | 2014-06-12 | — | — | US | disclosed |
| US-20120135057-A1 | ANTIPERSPIRANT COMPOSITIONS AND PRODUCTS HAVING A DISPERSED COOLING SENSATION AGENT AND METHODS FOR MAKING THE SAME | THE DIAL CORPORATION (US) | 2012-05-31 | — | — | US | disclosed |
| US-20120134947-A1 | ANTIPERSPIRANT COMPOSITIONS AND PRODUCTS HAVING COOLING SENSATION EFFECTS AND METHODS FOR MAKING THE SAME | THE DIAL CORPORATION (US) | 2012-05-31 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12601929-B2 | Contact lens | TRPM8, TRPM7, TRPM5 | EPHX1 3263/4885TRPM8 1/4885TRPA1 4/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.