Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES2 | O00748 | 4/20 | 0.38 |
| ▸ | THRB | P10828 | 2/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.38 |
| ▸ | GMNN | O75496 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | BLM | P54132 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | EPHX1 | P07099 | 3/20 | 0.34 |
| ▸ | CES1 | P23141 | 5/20 | 0.33 |
| ▸ | FAAH | O00519 | 4/20 | 0.33 |
| ▸ | CTSL | P07711 | 1/20 | 0.33 |
| ▸ | CTSB | P07858 | 1/20 | 0.33 |
| ▸ | PLA2G6 | O60733 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6841034 | 0.85 | TSHR (0.50) | CES2THRBHSD17B10TSHRLMNA | |
| SCHEMBL6841494 | 0.85 | TSHR (0.50) | CES2THRBHSD17B10TSHRLMNA | |
| SCHEMBL6841441 | 0.85 | TSHR (0.50) | CES2THRBHSD17B10TSHRLMNA | |
| SCHEMBL4293102 | 0.85 | TSHR (0.50) | CES2THRBHSD17B10TSHRLMNA | |
| SCHEMBL6841496 | 0.85 | TSHR (0.50) | CES2THRBHSD17B10TSHRLMNA | |
| SCHEMBL968834 | 0.85 | TSHR (0.50) | CES2THRBHSD17B10TSHRLMNA | |
| SCHEMBL968567 | 0.85 | TSHR (0.50) | CES2THRBHSD17B10TSHRLMNA | |
| SCHEMBL399173 | 0.83 | — | — | |
| SCHEMBL867481 | 0.80 | TSHR (0.57) | CES2THRBHSD17B10GMNNTP53 | |
| SCHEMBL9330272 | 0.80 | TSHR (0.57) | CES2THRBHSD17B10GMNNTP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2432827-B1 | RUBBER COMPOSITION INCLUDING AN ORGANOSILANE COUPLING AGENT | MICHELIN & CIE (FR) | 2016-04-13 | — | — | EP | disclosed |
| EP-2432786-B1 | ORGANOSILANE COUPLING AGENT | MICHELIN & CIE (FR) | 2015-05-13 | — | — | EP | disclosed |
| US-8987353-B2 | Rubber composition including an organosilane coupling agent | MICHELIN RECHERCHE ET TECHNIQUE S.A. (CH) | 2015-03-24 | — | — | US | disclosed |
| US-8987361-B2 | Organosilane coupling agent | MICHELIN RECHERCHE ET TECHNIQUE S.A. (CH) | 2015-03-24 | — | — | US | disclosed |
| US-20120165468-A1 | Organosilane Coupling Agent | MICHELIN RECHERCHE ET TECHNIQUE S.A. (CH) | 2012-06-28 | — | — | US | disclosed |
| US-20120157571-A1 | Rubber Composition Including an Organosilane Coupling Agent | MICHELIN RECHERCHE ET TECHNIQUE S.A. (CH) | 2012-06-21 | — | — | US | disclosed |
| EP-2432827-A1 | RUBBER COMPOSITION INCLUDING AN ORGANOSILANE COUPLING AGENT | Société de Technologie MICHELIN (FR) | 2012-03-28 | — | — | EP | disclosed |
| EP-2432786-A1 | ORGANOSILANE COUPLING AGENT | Société de Technologie MICHELIN (FR) | 2012-03-28 | — | — | EP | disclosed |
| WO-2010133371-A1 | RUBBER COMPOSITION INCLUDING AN ORGANOSILANE COUPLING AGENT | SOCIETE DE TECHNOLOGIE MICHELIN (FR) | 2010-11-25 | — | — | WO | disclosed |
| WO-2010133373-A1 | ORGANOSILANE COUPLING AGENT | SOCIETE DE TECHNOLOGIE MICHELIN (FR) | 2010-11-25 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120165468-A1 | Organosilane Coupling Agent | H1-2, C1S, HRH3 | CES2 2811/4885THRB 2963/4885HSD17B10 3575/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.