SCHEMBL968567

SCHEMBL968567

CCCCCCCCC[SiH](O)O

nearest known ligand 0.50

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
TSHR P16473 3/20 0.50
THRB P10828 1/20 0.50
LMNA P02545 2/20 0.45
ALDH1A1 P00352 2/20 0.45
MEN1 O00255 2/20 0.45
KMT2A Q03164 2/20 0.45
HSD17B10 Q99714 1/20 0.45
SMN1; SMN2 Q16637 1/20 0.40
CES2 O00748 3/20 0.39
CES1 P23141 3/20 0.39
EPHX1 P07099 2/20 0.39
DNM1 Q05193 5/20 0.38
SLC22A1 O15245 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6841034 1.00 TSHR (0.50) TSHRTHRBLMNAALDH1A1MEN1
SCHEMBL968834 1.00 TSHR (0.50) TSHRTHRBLMNAALDH1A1MEN1
SCHEMBL6841496 1.00 TSHR (0.50) TSHRTHRBLMNAALDH1A1MEN1
SCHEMBL6841494 1.00 TSHR (0.50) TSHRTHRBLMNAALDH1A1MEN1
SCHEMBL4293102 1.00 TSHR (0.50) TSHRTHRBLMNAALDH1A1MEN1
SCHEMBL6841441 1.00 TSHR (0.50) TSHRTHRBLMNAALDH1A1MEN1
SCHEMBL399173 0.97
SCHEMBL970152 0.87
SCHEMBL851446 0.85 CES2 (0.38) TSHRTHRBLMNAALDH1A1MEN1
SCHEMBL4521500 0.85 TSHR (0.59) TSHRALDH1A1EPHX1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9000092-B2 Rubber composition comprising a blocked mercaptosilane coupling agent COMPAGNIE GENERALE DES ETABLISSEMENTS MICHELIN (FR) 2015-04-07 US disclosed
EP-2379633-B1 RUBBER COMPOSITION COMPRISING A BLOCKED MERCAPTOSILANE COUPLING AGENT MICHELIN & CIE (FR) 2014-05-07 EP disclosed
US-20110306700-A1 RUBBER COMPOSITION COMPRISING A BLOCKED MERCAPTOSILANE COUPLING AGENT MICHELIN RECHERCHE ET TECHNIQUE S.A. (SE) 2011-12-15 US disclosed
EP-2379633-A1 RUBBER COMPOSITION COMPRISING A BLOCKED MERCAPTOSILANE COUPLING AGENT Société de Technologie MICHELIN (FR) 2011-10-26 EP disclosed
US-20110009547-A1 RUBBER COMPOSITION FOR A TYRE COMPRISING A HYDROXYSILANE COVERING AGENT COMPAGNIE GENERALE DES ETABLISSEMENTS MICHELIN (FR) 2011-01-13 US disclosed
EP-2212379-A2 RUBBER COMPOSITION FOR A TYRE COMPRISING A HYDROXYSILANE COVERING AGENT Société de Technologie MICHELIN (FR) 2010-08-04 EP disclosed
WO-2010072682-A1 RUBBER COMPOSITION COMPRISING A BLOCKED MERCAPTOSILANE COUPLING AGENT SOCIETE DE TECHNOLOGIE MICHELIN (FR) 2010-07-01 WO disclosed
WO-2009062733-A2 RUBBER COMPOSITION FOR A TYRE COMPRISING A HYDROXYSILANE COVERING AGENT SOCIETE DE TECHNOLOGIE MICHELIN (FR) 2009-05-22 WO disclosed