Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DHODH | Q02127 | 7/20 | 0.44 |
| ▸ | ACP1 | P24666 | 1/20 | 0.44 |
| ▸ | PTGFR | P43088 | 2/20 | 0.44 |
| ▸ | PDE10A | Q9Y233 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | IGF1R | P08069 | 1/20 | 0.39 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.38 |
| ▸ | SCN10A | Q9Y5Y9 | 1/20 | 0.38 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8515384 | 0.89 | ACP1 (0.44) | DHODHACP1PTGFRMAPTIGF1R | |
| SCHEMBL8515625 | 0.81 | ACP1 (0.45) | DHODHACP1PTGFRSCN10ATRPV1 | |
| SCHEMBL8514929 | 0.80 | DHODH (0.49) | DHODHACP1PTGFRPDE10ATSHR | |
| SCHEMBL8514932 | 0.80 | DHODH (0.49) | DHODHACP1PTGFRPDE10ATSHR | |
| SCHEMBL8515898 | 0.80 | CYP3A4 (0.43) | DHODHPTGFRSCN10A | |
| SCHEMBL8514255 | 0.78 | PDE10A (0.44) | DHODHACP1PTGFRPDE10ATSHR | |
| SCHEMBL8514251 | 0.78 | PDE10A (0.44) | DHODHACP1PTGFRPDE10ATSHR | |
| SCHEMBL8512120 | 0.75 | SCN9A (0.45) | DHODHACP1PTGFRPDE10AMAPT | |
| SCHEMBL23204079 | 0.72 | ALDH1A3 (0.51) | ACP1MAPT | |
| SCHEMBL6309767 | 0.71 | DHODH (0.70) | DHODHPTGFRPDE10ATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012069856-A1 | ANTIMALARIAL COMPOUNDS | LIVERPOOL SCHOOL OF TROPICAL MEDICINE (GB) | 2012-05-31 | — | — | WO | claimed |
| WO-2012069856-A1 | ANTIMALARIAL COMPOUNDS | LIVERPOOL SCHOOL OF TROPICAL MEDICINE (GB) | 2012-05-31 | — | — | WO | disclosed |
| WO-2012069856-A1 | ANTIMALARIAL COMPOUNDS | LIVERPOOL SCHOOL OF TROPICAL MEDICINE (GB) | 2012-05-31 | — | — | WO | disclosed |