SCHEMBL8514871

SCHEMBL8514871

Fc1cc(OC(F)(F)c2c(F)cc(Br)cc2F)cc(F)c1F

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28517740 0.98
SCHEMBL2395180 0.89
SCHEMBL91887 0.86 HDAC1 (0.30)
SCHEMBL18747195 0.85
SCHEMBL12358129 0.85 CES2 (0.32)
SCHEMBL14366258 0.84 ANPEP (0.33)
SCHEMBL9913188 0.83 ALOX5AP (0.38)
SCHEMBL12760431 0.83 ALOX5AP (0.36)
SCHEMBL24492676 0.82 TRPV4 (0.38)
SCHEMBL26453265 0.82

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 85 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116217354-B Efficient green synthesis method and product of liquid crystal monomer 烟台德润液晶材料有限公司 2025-02-11 CN claimed
CN-116217354-A Efficient green synthesis method and product of liquid crystal monomer 烟台德润液晶材料有限公司 2023-06-06 CN claimed
CN-115692851-A Functional electrolyte additive for lithium metal air battery 南京工业大学 2023-02-03 CN claimed
CN-115692851-B Functional electrolyte additive for lithium metal air battery 南京工业大学 2026-04-10 CN disclosed
CN-116217354-B Efficient green synthesis method and product of liquid crystal monomer 烟台德润液晶材料有限公司 2025-02-11 CN disclosed
CN-112811994-B Difluoro ether compound with 3-pentenyl end group and synthesis method thereof 江苏和成新材料有限公司 2024-02-02 CN disclosed
CN-116217354-A Efficient green synthesis method and product of liquid crystal monomer 烟台德润液晶材料有限公司 2023-06-06 CN disclosed
CN-112125788-B Preparation method of liquid crystal monomer compound containing difluoromethyl ether bridge bond 宁夏中星显示材料有限公司 2023-04-07 CN disclosed
CN-110790641-B Method for producing compound having oxydifluoromethylene skeleton 大金工业株式会社 2023-02-28 CN disclosed
CN-115692851-A Functional electrolyte additive for lithium metal air battery 南京工业大学 2023-02-03 CN disclosed
CN-115692851-A Functional electrolyte additive for lithium metal air battery 南京工业大学 2023-02-03 CN disclosed
US-20100237285-A1 CYCLOHEXENE COMPOUNDS FOR LIQUID-CRYSTALLINE MIXTURES MERCK PATENT GESELLSCHAFT (DE) 2010-09-23 US disclosed
US-20100237285-A1 CYCLOHEXENE COMPOUNDS FOR LIQUID-CRYSTALLINE MIXTURES MERCK PATENT GESELLSCHAFT (DE) 2010-09-23 US disclosed
US-7344761-B2 Liquid-crystalline compounds MERCK PATENT GESELLASCHAFT MIT BESCHRANKTER HAFTUNG (DE) 2008-03-18 US disclosed
WO-2008019743-A1 CYCLOHEXENE COMPOUNDS FOR LIQUID-CRYSTALLINE MIXTURES MERCK PATENT GMBH (DE) 2008-02-21 WO disclosed
US-7314943-B2 Pyran derivatives containing an exocyclic double bond MERCK PATENT GMBH (DE) 2008-01-01 US disclosed
US-7291367-B2 Liquid-crystalline compounds MERCK PATENT GMBH (DE) 2007-11-06 US disclosed
US-7291367-B2 Liquid-crystalline compounds MERCK PATENT GMBH (DE) 2007-11-06 US disclosed
US-20070034828-A1 Containing 3 directly connected rings: a fluorophenyl ring, a tetrahydropyran ring and either another tetrahydropyran ring or a 1,3-dioxane ring; electrooptical displays; MERCK PATENT GMBH (DE) 2007-02-15 US disclosed
US-20070034828-A1 Containing 3 directly connected rings: a fluorophenyl ring, a tetrahydropyran ring and either another tetrahydropyran ring or a 1,3-dioxane ring; electrooptical displays; MERCK PATENT GMBH (DE) 2007-02-15 US disclosed