Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5AP | P20292 | 2/20 | 0.38 |
| ▸ | FEN1 | P39748 | 2/20 | 0.38 |
| ▸ | ERN1 | O75460 | 1/20 | 0.32 |
| ▸ | GPR3 | P46089 | 3/20 | 0.32 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.31 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.30 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2485987 | 0.92 | ALOX5AP (0.38) | ALOX5APFEN1ERN1GPR3GRM2 | |
| SCHEMBL12760431 | 0.92 | ALOX5AP (0.36) | ALOX5APFEN1 | |
| SCHEMBL15388222 | 0.88 | ALOX5AP (0.41) | ALOX5APFEN1ERN1GPR3GRM2 | |
| SCHEMBL17407700 | 0.87 | ALOX5AP (0.39) | ALOX5APFEN1ERN1GPR3GRM2 | |
| SCHEMBL18099489 | 0.86 | ERN1 (0.42) | ALOX5APFEN1ERN1GRM2FFAR1 | |
| SCHEMBL10021838 | 0.86 | ALOX5AP (0.38) | ALOX5APFEN1ERN1GPR3GRM2 | |
| SCHEMBL19557566 | 0.86 | ALOX5AP (0.38) | ALOX5APFEN1ERN1GPR3GRM2 | |
| SCHEMBL18750575 | 0.85 | ALOX5AP (0.38) | ALOX5APFEN1ERN1GPR3GRM2 | |
| SCHEMBL12357204 | 0.85 | GPR3 (0.40) | ALOX5APFEN1ERN1GPR3GRM2 | |
| SCHEMBL19465064 | 0.85 | ALOX5AP (0.38) | ALOX5APFEN1ERN1GPR3GRM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3156388-B1 | LIQUID CRYSTAL COMPOUND HAVING CF2O BONDING GROUP AND TOLANE BACKBONE, LIQUID CRYSTAL COMPOSITION, AND LIQUID CRYSTAL DISPLAY ELEMENT | JNC CORP (JP) | 2019-01-30 | — | — | EP | disclosed |
| US-9879183-B2 | Liquid crystal compound having CF2O bonding group and tolan skeleton, liquid crystal composition and liquid crystal display device | JNC CORPORATION (JP) | 2018-01-30 | — | — | US | disclosed |
| US-9657230-B2 | Alkenyl dioxane compound, liquid crystal composition and liquid crystal display device | JNC CORPORATION (JP) | 2017-05-23 | — | — | US | disclosed |
| US-9657230-B2 | Alkenyl dioxane compound, liquid crystal composition and liquid crystal display device | JNC CORPORATION (JP) | 2017-05-23 | — | — | US | disclosed |
| US-20170107427-A1 | LIQUID CRYSTAL COMPOUND HAVING CF2O BONDING GROUP AND TOLAN SKELETON, LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY DEVICE | JNC CORPORATION (JP) | 2017-04-20 | — | — | US | disclosed |
| US-20170107427-A1 | LIQUID CRYSTAL COMPOUND HAVING CF2O BONDING GROUP AND TOLAN SKELETON, LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY DEVICE | JNC CORPORATION (JP) | 2017-04-20 | — | — | US | disclosed |
| EP-3156388-A1 | LIQUID CRYSTAL COMPOUND HAVING CF2O BONDING GROUP AND TOLANE BACKBONE, LIQUID CRYSTAL COMPOSITION, AND LIQUID CRYSTAL DISPLAY ELEMENT | JNC Corporation (JP) | 2017-04-19 | — | — | EP | disclosed |
| US-20160280996-A1 | ALKENYL DIOXANE COMPOUND, LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY DEVICE | JNC CORPORATION (JP) | 2016-09-29 | — | — | US | disclosed |
| US-20160280996-A1 | ALKENYL DIOXANE COMPOUND, LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY DEVICE | JNC CORPORATION (JP) | 2016-09-29 | — | — | US | disclosed |
| EP-2319897-B1 | Liquid crystal compounds | MERCK PATENT GMBH (DE) | 2012-06-20 | — | — | EP | disclosed |
| US-8197709-B2 | Liquid-crystalline compounds | MERCK PATENT GESELLSCHAFT MIT BERSCHRANKTER HAFTUNG (DE) | 2012-06-12 | — | — | US | disclosed |
| US-8197709-B2 | Liquid-crystalline compounds | MERCK PATENT GESELLSCHAFT MIT BERSCHRANKTER HAFTUNG (DE) | 2012-06-12 | — | — | US | disclosed |
| EP-2319897-A1 | Liquid crystal compounds | Merck Patent GmbH (DE) | 2011-05-11 | — | — | EP | disclosed |
| US-20110101271-A1 | LIQUID-CRYSTALLINE COMPOUNDS | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 2011-05-05 | — | — | US | disclosed |
| US-20110101271-A1 | LIQUID-CRYSTALLINE COMPOUNDS | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 2011-05-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110101271-A1 | LIQUID-CRYSTALLINE COMPOUNDS | GJB2, GIGYF2, AQP3 | ALOX5AP 1645/4885FEN1 4228/4885ERN1 4168/4885 |
| US-20160280996-A1 | ALKENYL DIOXANE COMPOUND, LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY DEVICE | YBX1, PIEZO1, HAX1 | ALOX5AP 461/4885FEN1 744/4885ERN1 970/4885 |
| US-20170107427-A1 | LIQUID CRYSTAL COMPOUND HAVING CF2O BONDING GROUP AND TOLAN SKELETON, LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY DEVICE | PIEZO1, TLN1, TCOF1 | ALOX5AP 839/4885FEN1 1625/4885ERN1 853/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.