Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC2A1 | P11166 | 1/20 | 0.52 |
| ▸ | CCNB2 | O95067 | 1/20 | 0.49 |
| ▸ | CDK1 | P06493 | 1/20 | 0.49 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.49 |
| ▸ | CCNB3 | Q8WWL7 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.46 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.46 |
| ▸ | SERPINE1 | P05121 | 1/20 | 0.43 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.43 |
| ▸ | GCGR | P47871 | 1/20 | 0.43 |
| ▸ | MAPK12 | P53778 | 1/20 | 0.43 |
| ▸ | MAPK11 | Q15759 | 1/20 | 0.43 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.43 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.43 |
| ▸ | KIF11 | P52732 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29505903 | 0.83 | MAT2A (0.54) | KMT2AMAPTLMNAKDM4EPDE10A | |
| SCHEMBL8533470 | 0.83 | MAT2A (0.54) | KMT2AMAPTLMNAKDM4EPDE10A | |
| SCHEMBL10067341 | 0.79 | CCNB2 (0.63) | CCNB2CDK1CCNB1CCNB3KMT2A | |
| SCHEMBL8537070 | 0.78 | MAT2A (0.57) | SLC2A1KMT2ALMNAMEN1PTGS2 | |
| SCHEMBL8515371 | 0.77 | MAT2A (0.56) | KMT2AMAPTLMNAKDM4EPDE10A | |
| SCHEMBL18160172 | 0.77 | CCNB2 (0.53) | CCNB2CDK1CCNB1CCNB3KMT2A | |
| SCHEMBL8533456 | 0.77 | PTGS2 (0.52) | KMT2AMAPTLMNAMEN1PTGS2 | |
| SCHEMBL9607489 | 0.77 | HTT (0.48) | KMT2ALMNAMEN1PTGS2KDM4E | |
| SCHEMBL8534472 | 0.76 | KDM4E (0.50) | KMT2AMAPTLMNAMEN1PTGS2 | |
| SCHEMBL8020349 | 0.76 | PDE10A (0.64) | KMT2ALMNAMEN1PTGS2KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012069856-A1 | ANTIMALARIAL COMPOUNDS | LIVERPOOL SCHOOL OF TROPICAL MEDICINE (GB) | 2012-05-31 | — | — | WO | claimed |
| WO-2012069856-A1 | ANTIMALARIAL COMPOUNDS | LIVERPOOL SCHOOL OF TROPICAL MEDICINE (GB) | 2012-05-31 | — | — | WO | disclosed |