SCHEMBL8515210

SCHEMBL8515210

c1nc(CC2CCNC2)c[nH]1

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HRH3 Q9Y5N1 8/20 0.49
HRH4 Q9H3N8 6/20 0.49
SLC6A2 P23975 3/20 0.35
SLC6A4 P31645 3/20 0.35
SLC6A3 Q01959 1/20 0.35
SLC6A1 P30531 2/20 0.34
GABRA5 P31644 2/20 0.34
GABRB2 P47870 2/20 0.34
SLC6A12 P48065 2/20 0.34
SLC6A11 P48066 2/20 0.34
SLC6A13 Q9NSD5 2/20 0.34
GABRA1 P14867 1/20 0.34
GABRR1 P24046 1/20 0.34
GABRA4 P48169 1/20 0.34
ROCK2 O75116 2/20 0.34
ROCK1 Q13464 2/20 0.34
CDC42BPB Q9Y5S2 2/20 0.34
CDC42BPA Q5VT25 1/20 0.34
GBA1 P04062 1/20 0.33
KDM1A O60341 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15944212 0.90 HRH3 (0.51) HRH3HRH4ROCK2ROCK1CDC42BPB
Immepip SCHEMBL6347746 0.89 HRH3 (0.46) HRH3HRH4SLC6A4GBA1
Immepip SCHEMBL6605805 0.88 HRH3 (0.45) HRH3HRH4SLC6A4GBA1
Immepip SCHEMBL6354845 0.88 HRH3 (0.47) HRH3HRH4SLC6A4GBA1
SCHEMBL28079718 0.81
SCHEMBL14307810 0.78 HRH4 (0.42) HRH3HRH4
SCHEMBL6449281 0.77 HRH4 (0.44) HRH3HRH4
SCHEMBL6353897 0.76 HRH3 (0.49) HRH3HRH4SLC6A4GBA1
SCHEMBL1264781 0.74
SCHEMBL14140514 0.74 HRH3 (0.32) HRH3HRH4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240269123-A1 MUSCLE REGENERATION PROMOTER SATO PHARMACEUTICAL CO., LTD. (JP) 2024-08-15 US claimed
WO-2022255250-A1 MUSCLE REGENERATION PROMOTER 佐藤製薬株式会社 2022-12-08 WO claimed
US-20240269123-A1 MUSCLE REGENERATION PROMOTER SATO PHARMACEUTICAL CO., LTD. (JP) 2024-08-15 US disclosed
WO-2022255250-A1 MUSCLE REGENERATION PROMOTER 佐藤製薬株式会社 2022-12-08 WO disclosed
WO-1999031089-A1 1-(1H-IMIDAZOL-2-YL)PYRROLIDINE AND 1-(1H-IMIDAZOL-2-YLPIPERIDINE) DERIVATIVES, PREPARATION AND THERAPEUTIC APPLICATION SANOFI-SYNTHELABO (FR) 1999-06-24 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240269123-A1 MUSCLE REGENERATION PROMOTER MUSK, HRH3, HGF HRH3 2/4885HRH4 7/4885SLC6A2 1895/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.