Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 5/20 | 0.49 |
| ▸ | SLC6A4 | P31645 | 5/20 | 0.41 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.37 |
| ▸ | FAAH | O00519 | 1/20 | 0.35 |
| ▸ | GBA1 | P04062 | 1/20 | 0.33 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.33 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15139142 | 0.90 | HRH3 (0.51) | HRH3SLC6A4HRH4FAAHITGB3 | |
| Bromide SCHEMBL15130221 | 0.89 | HRH3 (0.50) | HRH3SLC6A4HRH4FAAHITGB3 | |
| SCHEMBL8524329 | 0.84 | HRH4 (0.41) | HRH3HRH4 | |
| Immepip SCHEMBL6347746 | 0.82 | HRH3 (0.46) | HRH3SLC6A4HRH4GBA1 | |
| Immepip SCHEMBL6354845 | 0.81 | HRH3 (0.47) | HRH3SLC6A4HRH4GBA1 | |
| Immepip SCHEMBL6605805 | 0.81 | HRH3 (0.45) | HRH3SLC6A4HRH4GBA1 | |
| SCHEMBL3207984 | 0.80 | GNAI3 (0.41) | HRH3HRH4 | |
| SCHEMBL8515210 | 0.76 | HRH3 (0.49) | HRH3SLC6A4HRH4GBA1 | |
| SCHEMBL9850899 | 0.75 | HRH4 (0.40) | HRH3HRH4 | |
| SCHEMBL7663603 | 0.74 | HRH3 (0.36) | HRH3FAAHITGB3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6951944-B2 | Production of imidazole derivatives and novel intermediates of the derivatives | AZWELL INC. (JP) | 2005-10-04 | — | — | US | disclosed |
| US-20050043277-A1 | Production of imidazole derivatives and novel intermediates of the derivatives | AZWELL INC. (JP) | 2005-02-24 | — | — | US | disclosed |
| EP-1477487-A1 | IMPROVEMENT IN THE PRODUCTION OF IMIDAZOLE DERIVATIVES AND NOVEL INTERMEDIATES OF THE DERIVATIVES | Azwell Inc. (JP) | 2004-11-17 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050043277-A1 | Production of imidazole derivatives and novel intermediates of the derivatives | HRH3, HRH4, HRH2 | HRH3 1/4885SLC6A4 2892/4885HRH4 2/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.