Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PAOX | Q6QHF9 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | DRD2 | P14416 | 6/20 | 0.37 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.37 |
| ▸ | CACNA1H | O95180 | 1/20 | 0.37 |
| ▸ | HTR1A | P08908 | 1/20 | 0.36 |
| ▸ | HTR7 | P34969 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.35 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bromide SCHEMBL5133205 | 0.96 | CYP1A2 (0.42) | PAOXCYP1A2MAPK1SMN1; SMN2DRD2 | |
| SCHEMBL16656264 | 0.93 | PAOX (0.44) | PAOXCYP1A2MAPK1SMN1; SMN2DRD2 | |
| Bromide SCHEMBL5132382 | 0.91 | CYP1A2 (0.47) | PAOXCYP1A2MAPK1SMN1; SMN2DRD2 | |
| SCHEMBL16656254 | 0.89 | CYP1A2 (0.45) | PAOXCYP1A2MAPK1SMN1; SMN2DRD2 | |
| SCHEMBL15938241 | 0.88 | GLA (0.43) | CYP1A2MAPK1SMN1; SMN2DRD2SIGMAR1 | |
| SCHEMBL20678135 | 0.88 | GLA (0.43) | CYP1A2MAPK1SMN1; SMN2DRD2SIGMAR1 | |
| SCHEMBL18379336 | 0.83 | GNAI3 (0.42) | PAOXDRD2HTR1ALMNA | |
| Bromide SCHEMBL5133207 | 0.83 | PAOX (0.39) | PAOXDRD2SIGMAR1CACNA1HHTR1A | |
| SCHEMBL6014048 | 0.82 | ADRA1A (0.42) | SMN1; SMN2SIGMAR1CACNA1HLMNA | |
| SCHEMBL25575666 | 0.82 | ADRA1A (0.42) | SMN1; SMN2SIGMAR1CACNA1HLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3242691-A1 | RADIOSENSITIVITY OF FLUOROPHORES AND USE OF RADIOPROTECTIVE AGENTS FOR DUAL-MODALITY IMAGING | Immunomedics, Inc. (US) | 2017-11-15 | — | — | EP | disclosed |
| US-20170283442-A1 | Methods and Compositions for Improved F-18 Labeling of Proteins, Peptides and Other Molecules | IMMUNOMEDICS, INC. | 2017-10-05 | — | — | US | disclosed |
| EP-3218015-A2 | METHODS AND COMPOSITIONS FOR IMPROVED LABELING OF TARGETING PEPTIDES | Immunomedics, Inc. (US) | 2017-09-20 | — | — | EP | disclosed |
| US-20170007727-A1 | METHODS OF IMAGING WITH Ga-68 LABELED MOLECULES | IMMUNOMEDICS, INC. | 2017-01-12 | — | — | US | disclosed |
| WO-2016111797-A1 | RADIOSENSITIVITY OF FLUOROPHORES AND USE OF RADIOPROTECTIVE AGENTS FOR DUAL-MODALITY IMAGING | IMMUNOMEDICS, INC. (US) | 2016-07-14 | — | — | WO | disclosed |
| US-20160199524-A1 | RADIOSENSITIVITY OF FLUOROPHORES AND USE OF RADIOPROTECTIVE AGENTS FOR DUAL-MODALITY IMAGING | IMMUNOMEDICS, INC. | 2016-07-14 | — | — | US | disclosed |
| WO-2016077061-A2 | METHODS AND COMPOSITIONS FOR IMPROVED LABELING OF TARGETING PEPTIDES | IMMUNOMEDICS, INC. (US) | 2016-05-19 | — | — | WO | disclosed |
| US-20160045626-A1 | Methods and Compositions for Improved Labeling of Targeting Peptides | IMMUNOMEDICS, INC. | 2016-02-18 | — | — | US | disclosed |
| US-20150307524-A1 | Methods and Compositions for Improved F-18 Labeling of Proteins, Peptides and Other Molecules | IMMUNOMEDICS, INC. | 2015-10-29 | — | — | US | disclosed |
| US-9115172-B2 | Methods and compositions for improved F-18 labeling of proteins, peptides and other molecules | IMMUNOMEDICS, INC. (US) | 2015-08-25 | — | — | US | disclosed |
| US-8889100-B2 | Methods and compositions for improved F-18 labeling of proteins, peptides and other molecules | IMMUNOMEDICS, INC. (US) | 2014-11-18 | — | — | US | disclosed |
| US-20140228541-A1 | Methods and Compositions for Improved F-18 Labeling of Proteins, Peptides and Other Molecules | IMMUNOMEDICS, INC. (US) | 2014-08-14 | — | — | US | disclosed |
| US-8758726-B2 | Methods and compositions for improved F-18 labeling of proteins, peptides and other molecules | IMMUNOMEDICS, INC. (US) | 2014-06-24 | — | — | US | disclosed |
| US-8709382-B2 | Methods and compositions for improved F-18 labeling of proteins, peptides and other molecules | IMMUNOMEDICS, INC. (US) | 2014-04-29 | — | — | US | disclosed |
| US-20140017168-A1 | Methods and Compositions for Improved F-18 Labeling of Proteins, Peptides and Other Molecules | IMMUNOMEDICS, INC. (US) | 2014-01-16 | — | — | US | disclosed |
| US-20130315821-A1 | Methods and Compositions for Improved F-18 Labeling of Proteins, Peptides and Other Molecules | IMMUNOMEDICS, INC. (US) | 2013-11-28 | — | — | US | disclosed |
| EP-2651411-A2 | METHODS AND COMPOSITIONS FOR IMPROVED F-18 LABELING OF PROTEINS, PEPTIDES AND OTHER MOLECULES | Immunomedics, Inc. (US) | 2013-10-23 | — | — | EP | disclosed |
| US-8545809-B2 | Methods and compositions for improved 18F labeling of proteins, peptides and other molecules | IMMUNOMEDICS, INC. (US) | 2013-10-01 | — | — | US | disclosed |
| WO-2012082618-A2 | METHODS AND COMPOSITIONS FOR IMPROVED F-18 LABELING OF PROTEINS, PEPTIDES AND OTHER MOLECULES | IMMUNOMEDICS, INC. (US) | 2012-06-21 | — | — | WO | disclosed |
| US-20120134920-A1 | Methods and Compositions for Improved F-18 Labeling of Proteins, Peptides and Other Molecules | IMMUNOMEDICS, INC. (US) | 2012-05-31 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (9 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130315821-A1 | Methods and Compositions for Improved F-18 Labeling of Proteins, Peptides and Other Molecules | F13B, PAICS, MRPL19 | PAOX 3991/4885CYP1A2 4873/4885MAPK1 4605/4885 |
| US-20160199524-A1 | RADIOSENSITIVITY OF FLUOROPHORES AND USE OF RADIOPROTECTIVE AGENTS FOR DUAL-MODALITY IMAGING | BRS3, BRCA1, MRE11 | PAOX 3920/4885CYP1A2 4315/4885MAPK1 4191/4885 |
| US-20120134920-A1 | Methods and Compositions for Improved F-18 Labeling of Proteins, Peptides and Other Molecules | F13B, FCGRT, PAICS | PAOX 3766/4885CYP1A2 4880/4885MAPK1 4667/4885 |
| US-20140228541-A1 | Methods and Compositions for Improved F-18 Labeling of Proteins, Peptides and Other Molecules | F13B, PAICS, MRPL19 | PAOX 3991/4885CYP1A2 4873/4885MAPK1 4605/4885 |
| US-20170007727-A1 | METHODS OF IMAGING WITH Ga-68 LABELED MOLECULES | BSG, HBG1, HBG2 | PAOX 2861/4885CYP1A2 4302/4885MAPK1 3763/4885 |
| US-20140017168-A1 | Methods and Compositions for Improved F-18 Labeling of Proteins, Peptides and Other Molecules | F13B, FCGRT, PAICS | PAOX 3766/4885CYP1A2 4880/4885MAPK1 4667/4885 |
| US-20150307524-A1 | Methods and Compositions for Improved F-18 Labeling of Proteins, Peptides and Other Molecules | F13B, PAICS, MRPL19 | PAOX 3991/4885CYP1A2 4873/4885MAPK1 4605/4885 |
| US-20160045626-A1 | Methods and Compositions for Improved Labeling of Targeting Peptides | SSTR5, SSTR4, SSTR2 | PAOX 3173/4885CYP1A2 4552/4885MAPK1 2586/4885 |
| US-20170283442-A1 | Methods and Compositions for Improved F-18 Labeling of Proteins, Peptides and Other Molecules | F13B, PAICS, MRPL19 | PAOX 3991/4885CYP1A2 4873/4885MAPK1 4605/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.