Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA1A | P35348 | 1/20 | 0.42 |
| ▸ | EPHX2 | P34913 | 4/20 | 0.42 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.41 |
| ▸ | CACNA1H | O95180 | 1/20 | 0.41 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.41 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.39 |
| ▸ | CHRM4 | P08173 | 2/20 | 0.39 |
| ▸ | CHRM5 | P08912 | 2/20 | 0.39 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.39 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.38 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | GFER | P55789 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6014048 | 1.00 | ADRA1A (0.42) | ADRA1AEPHX2SIGMAR1CACNA1HPRMT1 | |
| SCHEMBL31399675 | 0.89 | SIGMAR1 (0.44) | SIGMAR1CACNA1HALDH1A1TDP1LMNA | |
| SCHEMBL15047573 | 0.88 | ALDH1A1 (0.45) | SIGMAR1CACNA1HALDH1A1TDP1LMNA | |
| SCHEMBL28779145 | 0.88 | CHRM2 (0.42) | ADRA1AEPHX2SIGMAR1CACNA1HPRMT1 | |
| SCHEMBL13131284 | 0.86 | FOLH1 (0.37) | EPHX2SIGMAR1CACNA1HCHRM2CHRM4 | |
| SCHEMBL25729888 | 0.85 | TDP1 (0.51) | EPHX2SIGMAR1CACNA1HALDH1A1TDP1 | |
| SCHEMBL7130844 | 0.85 | ALDH1A1 (0.53) | SIGMAR1CACNA1HALDH1A1TDP1LMNA | |
| SCHEMBL13131283 | 0.85 | EPHX2 (0.47) | EPHX2FOLH1 | |
| SCHEMBL14678916 | 0.85 | SIGMAR1 (0.41) | EPHX2SIGMAR1CACNA1HALDH1A1TDP1 | |
| SCHEMBL15775091 | 0.84 | ALDH1A1 (0.42) | SIGMAR1CACNA1HALDH1A1TDP1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230302164-A1 | PSMA-Targeting Ligands With Optimal Properties for Imaging and Therapy | WISCONSIN ALUMNI RESEARCH FOUNDATION | 2023-09-28 | — | — | US | disclosed |
| US-20230173112-A1 | PSMA-Targeting Ligands With Optimal Properties for Imaging and Therapy | WISCONSIN ALUMNI RESEARCH FOUNDATION | 2023-06-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230173112-A1 | PSMA-Targeting Ligands With Optimal Properties for Imaging and Therapy | PSMA1, PSMA2, FOLH1 | ADRA1A 1062/4885EPHX2 4594/4885SIGMAR1 1557/4885 |
| US-20230302164-A1 | PSMA-Targeting Ligands With Optimal Properties for Imaging and Therapy | PSMA1, PSMA2, FOLH1 | ADRA1A 887/4885EPHX2 4667/4885SIGMAR1 1442/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.